
Arkafudic Cream
Arka Vital Science Private Limited. - Cream - 10 G
Save ₹5
Prescription required
Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Trempride Cream is used for melasma.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Trempride Cream contains Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w). It belongs to the Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic class of medicines.
Melasma
Trempride Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). Hydroquinone is a skin lightening medicine. It reduces the amount of a skin pigment (melanin) that causes darkening of skin. Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly. Fluocinolone acetonide is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. It is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Trempride are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Trempride Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. |
|---|---|
| Breastfeeding | Trempride Cream is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Alcohol | None No interaction found/established |
| Driving | Not expected to affect your ability to drive. |
| Kidney | None No interaction found/established |
| Liver | None No interaction found/established |
| Habit forming | No |
Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted. For external use only, unless the pack says otherwise. Stop if the skin becomes more irritated, and see a doctor if the condition worsens or spreads. Do a small test patch first if you have sensitive skin. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes. Not for use on broken or infected skin unless prescribed. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.
No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
Apply a thin layer — a fingertip's worth covers an area about the size of two adult palms. Use a plain moisturiser generously alongside it; that is what keeps eczema away between flares. Ask your doctor for a written plan of how long to use it and when to step down. Apply a thin layer to clean, dry skin. Wash your hands after use. Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.
Medicines with the same active ingredient (Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Trempride Cream |
|---|---|---|---|
| GlomelaIntas Pharmaceuticals Ltd | 20GM | ₹323 | 706% more |

Arka Vital Science Private Limited. - Cream - 10 G
Save ₹5
Prescription required
20 G
Save ₹6
Prescription required

East West Pharma - Ointment - 0.05%W/W + 3%W/W - 15 G
Save ₹5
Prescription required
Zydus Healthcare Pharma - Lotion - 0.05%W/W + 3.5%W/W - 20 ml
Save ₹11
Prescription required

Klm Lab - Cream - 0.05%W/W - 20 G
Save ₹14
Prescription required

24C Derma Labs - Cream - 0.05%W/W - 20 G
Save ₹10
Prescription required

Klm Lab - Cream - 0.05%W/W - 10 G
Save ₹7
Prescription required

Galderma India Pvt Ltd - Lotion - 0.05%W/W - 30 ml
Save ₹16
Prescription required

Dr Reddys Laboratories Ltd - Syrup - 60 ml
Save ₹19

Raptokos & Brett - Powder - 400 G

Dr Reddys Laboratories Ltd - Spray - 6 G
Save ₹59
Prescription required
Torrent Pharmaceuticals Ltd - Powder - 1 G
Save ₹3
Prescription required

Mankind (Pharma) - Syrup - 50 ml
Save ₹9
Prescription required

Gel - 10 ml

Glaxo Smithkline Pharma - Tablet - 1 Tablet
Save ₹2
Prescription required

German Remedies - Ointment - 50 G
Save ₹6
Prescription required
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.