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Prescription requiredTopical corticosteroid, Dermatological agent and Anti-acne agent

Trempride Cream

Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

Trempride Cream is used for melasma.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)
Available variants: cream 0.01%w/w + 2%w/w + 0.025%w/w 15GM
Best price: ₹40 (₹2.67 per g)
MRP: ₹42
Prescription: Required
Manufacturer: C

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Trempride Cream

Trempride Cream contains Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w). It belongs to the Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic class of medicines.

Uses of Trempride Cream

Melasma

Key benefits

  • Rapid relief of itching and inflammation
  • Acts where it is applied
  • Clears and prevents acne
  • Improves skin texture and marks over time

How Trempride Cream works

Trempride Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). Hydroquinone is a skin lightening medicine. It reduces the amount of a skin pigment (melanin) that causes darkening of skin. Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly. Fluocinolone acetonide is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.

How to take Trempride Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. It is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Trempride Cream

Most side effects of Trempride are mild and settle as the body adjusts. Reported side effects include:

  • Erythema (skin redness)
  • Skin peeling
  • Burning sensation
  • Dryness
  • Itching
  • Acne
  • Dryness in mouth

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Trempride Cream

PregnancyTrempride Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingTrempride Cream is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
AlcoholNone No interaction found/established
DrivingNot expected to affect your ability to drive.
KidneyNone No interaction found/established
LiverNone No interaction found/established
Habit formingNo

Warnings and precautions

Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted. For external use only, unless the pack says otherwise. Stop if the skin becomes more irritated, and see a doctor if the condition worsens or spreads. Do a small test patch first if you have sensitive skin. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds.

Do not take Trempride if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes. Not for use on broken or infected skin unless prescribed. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.

Interactions with other medicines

No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.

How to store Trempride Cream

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Expert advice for Trempride Cream

Apply a thin layer — a fingertip's worth covers an area about the size of two adult palms. Use a plain moisturiser generously alongside it; that is what keeps eczema away between flares. Ask your doctor for a written plan of how long to use it and when to step down. Apply a thin layer to clean, dry skin. Wash your hands after use. Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.

Manufacturer and class

Manufacturer:
C
Therapeutic class:
Topical corticosteroid, Dermatological agent and Anti-acne agent
Drug class:
Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic

Substitutes for Trempride Cream

Medicines with the same active ingredient (Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Trempride Cream
GlomelaIntas Pharmaceuticals Ltd20GM₹323706% more
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Trempride Cream FAQs

What is Trempride Cream used for?
Trempride Cream is commonly used for Melasma. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Trempride Cream?
Trempride Cream contains Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Trempride Cream?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Trempride Cream work?
Trempride Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin).
Is Trempride Cream a prescription medicine?
Yes. Trempride Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Trempride Cream?
The side effects reported most often with Trempride are Erythema (skin redness), Skin peeling, Burning sensation, Dryness, Itching. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Trempride Cream be taken during pregnancy?
Trempride Cream may be unsafe to use during pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Trempride.
Can I drink alcohol while taking Trempride Cream?
None No interaction found/established
What if I miss a dose of Trempride Cream?
Apply it as soon as you remember.
Is Trempride Cream habit forming?
No. Trempride Cream is not known to be habit forming when taken as prescribed.
How much does Trempride Cream cost on PingMeDoc Pharmacy?
Trempride Cream starts at ₹40 (MRP ₹42) on PingMeDoc Pharmacy. Available in cream 0.01%w/w + 2%w/w + 0.025%w/w 15GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Trempride Cream?
Trempride Cream is manufactured by C. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Trempride Cream delivered?
Trempride Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Trempride Cream, Quick facts

Salt
Fluocinolone (0.01%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)
Form
cream
Best price
₹40 (₹2.67 per g)
MRP
₹42
Prescription
Required (Rx)
Manufacturer
C
Therapeutic class
Topical corticosteroid, Dermatological agent and Anti-acne agent
Drug class
Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic
Habit forming
No
Variants
cream 0.01%w/w + 2%w/w + 0.025%w/w 15GM
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Trempride Cream.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.