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Prescription requiredTorrent Pharmaceuticals LtdNEURO CNS

Trika Plus Tablet

Alprazolam (0.5mg) + Sertraline (25mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹37

Trika Plus Tablet is used for depression.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Alprazolam (0.5mg) + Sertraline (25mg)
Available variants: tablet 0.5mg + 25mg 10`S
Best price: ₹37 (₹3.75 per tablet)
MRP: ₹39
Prescription: Required
Manufacturer: TORRENT PHARMACEUTICALS

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Trika Plus Tablet

Trika Plus Tablet contains Alprazolam (0.5mg) + Sertraline (25mg). It belongs to the Benzodiazepine / sedative-hypnotic and Antidepressant class of medicines.

Uses of Trika Plus Tablet

Depression

Key benefits

  • In Depression Trika Plus 0.5 mg/25 mg Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing
  • relieve anxiety and tension
  • helps you sleep better
  • and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

How Trika Plus Tablet works

Trika Plus 0.5 mg/25 mg Tablet is a combination of two medicines:

How to take Trika Plus Tablet

Take exactly as prescribed by your doctor.

Side effects of Trika Plus Tablet

Most side effects of Trika Plus are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Trika Plus Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver UNSAFE
Habit formingYes

Warnings and precautions

These medicines cause dependence. They are intended for the shortest possible course — usually two to four weeks — and are not a long-term treatment for anxiety or sleeplessness. Never stop a regular course suddenly. Withdrawal can cause severe anxiety, tremor and fits. Your doctor will taper it slowly. Do not drive or operate machinery. Drowsiness and slowed reactions can continue into the next day. Never combine with alcohol or with opioid painkillers — together they can stop your breathing. Older people are far more likely to fall, become confused or have memory problems on these medicines. Several of these are Schedule H1 medicines and must be dispensed against a prescription and entered in the pharmacy register. These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Do not take Trika Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe breathing problems, sleep apnoea, or severe liver disease. Not for anyone with a history of dependence, except under specialist supervision. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Alcohol, opioids, antihistamines, muscle relaxants and other sedatives all deepen the sedation, sometimes fatally. Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

How to store Trika Plus Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Trika Plus Tablet

Trika Plus 0.5 mg/25 mg Tablet is prescribed for the treatment of depression. Inform your doctor immediately if you get thoughts about harming yourself or ending your life. It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood. Do not stop taking Trika Plus 0.5 mg/25 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary. Avoid the use of Trika Plus 0.5 mg/25 mg Tablet along with certain medications like aspirin, warfarin, ibuprofen, or naproxen as it might increase the risk of bleeding. Inform your doctor if you observe changes in appetite or weight. Inform your doctor if you are taking any other antidepressant. If you have diabetes, you will be asked to monitor your blood glucose level regularly as Trika Plus 0.5 mg/25 mg Tablet may affect the levels of sugar in your blood. Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Manufacturer and class

Manufacturer:
TORRENT PHARMACEUTICALS
Therapeutic class:
NEURO CNS
Drug class:
Benzodiazepine / sedative-hypnotic and Antidepressant

Substitutes for Trika Plus Tablet

Medicines with the same active ingredient (Alprazolam (0.5mg) + Sertraline (25mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Trika Plus Tablet
Anxit PlusMICRO LABS10`S₹85126% more
Alprax Plus TabletTorrent Pharmaceuticals Ltdtablet · 10`S₹91142% more
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Trika Plus Tablet FAQs

What is Trika Plus Tablet used for?
Trika Plus Tablet is commonly used for Depression. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Trika Plus Tablet?
Trika Plus Tablet contains Alprazolam (0.5mg) + Sertraline (25mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How does Trika Plus Tablet work?
Trika Plus 0.5 mg/25 mg Tablet is a combination of two medicines:
Is Trika Plus Tablet a prescription medicine?
Yes. Trika Plus Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Trika Plus Tablet?
The side effects reported most often with Trika Plus are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Trika Plus Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Trika Plus.
Can I drink alcohol while taking Trika Plus Tablet?
Alcohol UNSAFE
Is Trika Plus Tablet habit forming?
Yes Take Trika Plus only as directed and for the duration your doctor advises.
How much does Trika Plus Tablet cost on PingMeDoc Pharmacy?
Trika Plus Tablet starts at ₹37 (MRP ₹39) on PingMeDoc Pharmacy. Available in tablet 0.5mg + 25mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Trika Plus Tablet?
Trika Plus Tablet is manufactured by TORRENT PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Trika Plus Tablet delivered?
Trika Plus Tablet is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Trika Plus Tablet, Quick facts

Salt
Alprazolam (0.5mg) + Sertraline (25mg)
Form
tablet
Best price
₹37 (₹3.75 per tablet)
MRP
₹39
Prescription
Required (Rx)
Schedule
Schedule H1
Brand
Torrent Pharmaceuticals Ltd
Manufacturer
TORRENT PHARMACEUTICALS
Therapeutic class
NEURO CNS
Drug class
Benzodiazepine / sedative-hypnotic and Antidepressant
Habit forming
Yes
Variants
tablet 0.5mg + 25mg 10`S
Delivery
Standard across India

References

The information on Trika Plus Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Trika Plus Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.