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Prescription requiredAlkem LabAntiepileptic
Valkem OD 1000 mg Tablet
Divalproex (1000mg)
₹262MRP ₹2765% offIn stock
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Valkem OD 1000 mg Tablet is used for treatment of epilepsy/seizure disorders (generalised and partial seizures); management of bipolar disorder (acute mania and maintenance) as prescribed; prevention of migraine (when prescribed).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Divalproex (1000mg)
Available variants: tablet 1000 mg 10`S
Best price: ₹262 (₹26.19 per tablet)
MRP: ₹276
Prescription: Required
Manufacturer: ALKEM LAB
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Valkem OD 1000 mg Tablet
Valkem OD 1000 mg Tablet contains Divalproex (1000mg). It belongs to the Anticonvulsant (valproate; GABA enhancer) class of medicines.
Uses of Valkem OD 1000 mg Tablet
- Epilepsy
- Seizure disorders (generalised
- Partial seizures)
- Management of bipolar disorder (acute mania
- Maintenance) as prescribed
- Prevention of migraine (when prescribed)
Benefits of Valkem OD 1000 mg Tablet
- In Epilepsy
- Valkem OD steadies the electrical activity in the brain so that seizures happen less often or stop altogether. Taking it at the same time every day is what keeps you protected.
- In Seizures
- Valkem OD raises the threshold at which a seizure can start, preventing fits and the injuries and loss of consciousness they cause.
- In Bipolar disorder
- Valkem OD evens out the extreme highs and lows of bipolar disorder and helps prevent episodes coming back.
- In Migraine prevention
- Valkem OD, taken daily, reduces the number and severity of migraine attacks.
How Valkem OD 1000 mg Tablet works
Valproate increases the levels of the inhibitory neurotransmitter GABA and also modulates sodium and calcium channels in the brain. This stabilizes neuronal firing and helps prevent seizures and mood swings.
How to take Valkem OD 1000 mg Tablet
Tablet (OD/prolonged-release): take exactly as prescribed, usually once daily at the same time. Swallow whole with water; do not crush/chew/split prolonged-release tablets. Preferably take with food to reduce stomach upset.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Valkem OD 1000mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine can cause deep unconsciousness, slowed breathing and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Valkem OD 1000 mg Tablet
Most side effects of Valkem OD are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Nausea
- vomiting
- stomach pain
- diarrhoea
- loss of appetite
- weight gain
- tremor
- dizziness
- drowsiness
- headache
- hair loss
- increased liver enzymes
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Valkem OD 1000 mg Tablet
- AlcoholUNSAFE
- Do not drink alcohol while taking this medicine.
- PregnancyUNSAFE
- Not recommended (high risk of birth defects and neurodevelopmental disorders); use only if no suitable alternative and under specialist supervision
- Breast feedingUNSAFE
- Not recommended while breastfeeding.
- DrivingUNSAFE
- Do not drive or operate machinery while taking this medicine.
- KidneyCONSULT YOUR DOCTOR
- Consult your doctor if you have kidney disease.
- LiverUNSAFE
- Not recommended if you have significant liver disease.
Warnings and precautions
Prescription-only medicine. Risk of serious liver injury (especially in first 6 months), pancreatitis, and hyperammonaemia—seek urgent care for severe abdominal pain, persistent vomiting, jaundice, confusion, unusual bruising/bleeding. May cause drowsiness—avoid driving if affected. Monitor liver function tests, platelet count and valproate levels as advised. Use caution in patients with liver disease, bleeding disorders, mitochondrial disorders (POLG), and in children. Do not stop abruptly without medical advice.
Do not take Valkem OD if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Valproate-containing medicines are contraindicated in pregnancy for epilepsy unless no alternative exists, and in all women of childbearing potential without a pregnancy prevention programme. Several are not suitable in significant liver disease.
Interactions with other medicines
Alcohol (additive sedation), lamotrigine (increases lamotrigine levels/risk of rash), carbamazepine/phenytoin/phenobarbital (altered levels), topiramate (risk of hyperammonaemia/encephalopathy), aspirin/NSAIDs and warfarin (increased bleeding risk), rifampicin (reduced valproate levels), antidepressants/benzodiazepines (additive CNS depression)
How to store Valkem OD 1000 mg Tablet
Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.
Quick tips for Valkem OD 1000 mg Tablet
- Take your medication regularly as directed by your doctor, as missing doses can trigger seizures.
- Take it at the same time every day to maintain consistent levels in your body.
- It can be taken with or without food; however, consider taking it with food to avoid an upset stomach.
- Do not change the brand of your medicine, and make sure that you have a sufficient amount of medicine present with you.
- It may cause dizziness and sleepiness.
- Do not drive or do anything that requires mental focus until you know how it affects you.
- Monitor your weight during treatment with this medicine, as it can cause weight gain.
- Your doctor may get regular blood tests done to monitor how the medication is affecting your body.
Related lab tests
People taking Valkem OD are often asked to check these from time to time. Your doctor decides which and how often.
Manufacturer and class
- Manufacturer:
- ALKEM LAB
- Therapeutic class:
- Antiepileptic
- Drug class:
- Anticonvulsant (valproate; GABA enhancer)
- Chemical class:
- Methyl- branched fatty acids
Substitutes for Valkem OD 1000 mg Tablet
Medicines with the same active ingredient (Divalproex (1000mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Valkem OD 1000 mg Tablet |
|---|---|---|---|
| Divalex OD 1000 mg TabletCRESCENT FORUMULATIONS PVT LTD | tablet · 10`S | ₹269 | 3% more |
| Dayo OD 1 g TabletLUPIN LAB | tablet · 10`S | ₹272 | 4% more |
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Valkem OD 1000 mg Tablet FAQs
What is Valkem OD 1000 mg Tablet used for?
Valkem OD 1000 mg Tablet is commonly used for Treatment of epilepsy/seizure disorders (generalised and partial seizures); management of bipolar disorder (acute mania and maintenance) as prescribed; prevention of migraine (when prescribed). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Valkem OD 1000 mg Tablet?
Epilepsy: Valkem OD steadies the electrical activity in the brain so that seizures happen less often or stop altogether. Taking it at the same time every day is what keeps you protected. It is also used for seizures, bipolar disorder, migraine prevention.
What is the salt in Valkem OD 1000 mg Tablet?
Valkem OD 1000 mg Tablet contains Divalproex (1000mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Valkem OD 1000 mg Tablet?
Tablet (OD/prolonged-release): take exactly as prescribed, usually once daily at the same time. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Valkem OD 1000 mg Tablet work?
Valproate increases the levels of the inhibitory neurotransmitter GABA and also modulates sodium and calcium channels in the brain.
Is Valkem OD 1000 mg Tablet a prescription medicine?
Yes. Valkem OD 1000 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Valkem OD 1000 mg Tablet?
The side effects reported most often with Valkem OD are Nausea, vomiting, stomach pain, diarrhoea, loss of appetite. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Valkem OD 1000 mg Tablet be taken during pregnancy?
Valkem OD 1000 mg Tablet is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Valkem OD.
Can I drink alcohol while taking Valkem OD 1000 mg Tablet?
No. Do not drink alcohol while taking Valkem OD 1000 mg Tablet.
What if I miss a dose of Valkem OD 1000 mg Tablet?
If you miss a dose of Valkem OD 1000mg Tablet, take it as soon as possible.
Is Valkem OD 1000 mg Tablet habit forming?
No. Valkem OD 1000 mg Tablet is not known to be habit forming when taken as prescribed.
How much does Valkem OD 1000 mg Tablet cost on PingMeDoc Pharmacy?
Valkem OD 1000 mg Tablet starts at ₹262 (MRP ₹276) on PingMeDoc Pharmacy. Available in tablet 1000 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Valkem OD 1000 mg Tablet?
Valkem OD 1000 mg Tablet is manufactured by ALKEM LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Valkem OD 1000 mg Tablet delivered?
Valkem OD 1000 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Valkem OD 1000 mg Tablet, Quick facts
- Salt
- Divalproex (1000mg)
- Form
- tablet
- Best price
- ₹262 (₹26.19 per tablet)
- MRP
- ₹276
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- ALKEM LAB
- Manufacturer
- ALKEM LAB
- Therapeutic class
- Antiepileptic
- Drug class
- Anticonvulsant (valproate; GABA enhancer)
- Chemical class
- Methyl- branched fatty acids
- Action class
- Sodium Channel Modulators- Antiepileptic drugs (AEDs)
- Habit forming
- No
- Variants
- tablet 1000 mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- Manufacturer labeling/pack insert
- CDSCO prescribing information norms, established medical literature (e.g.
- BNF/DrugBank), standard clinical guidelines for valproate
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Valkem OD 1000 mg Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.