Valrate CR 300

Composition of Valrate CR 300

Valrate CR 300 contains Sodium Valproate (200mg) + Valproic Acid (87mg). It belongs to the Anticonvulsant (Valproate; GABA-enhancing agent) class of medicines.

Uses of Valrate CR 300

Treatment of epilepsy/seizure disorders (including generalized and partial seizures); prevention of migraine (as prescribed); may also be used for bipolar disorder/mania under specialist care

Key benefits

• Helps control and prevent seizures
• Stabilizes abnormal electrical activity in the brain
• Convenient controlled-release dosing
• May help prevent migraine attacks (when prescribed)
• Supports long-term epilepsy management

How Valrate CR 300 works

Sodium valproate increases brain levels of the inhibitory neurotransmitter GABA and modulates neuronal ion channels, which stabilizes abnormal electrical activity in the brain. This helps prevent and control seizures and reduces neuronal hyperexcitability.

How to take Valrate CR 300

Oral controlled-release tablet: take exactly as prescribed, preferably at the same time each day. Swallow whole with water; do not crush, chew, or break. Can be taken with food to reduce stomach upset.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause deep unconsciousness, slowed breathing and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Valrate CR 300

Most side effects of Valrate CR are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• stomach pain
• indigestion
• diarrhea
• increased appetite
• weight gain
• dizziness
• drowsiness
• tremor
• hair loss
• headache

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Valrate CR 300

Warnings and precautions

Prescription medicine. Risk of serious liver injury and pancreatitis—seek urgent care for severe abdominal pain, persistent vomiting, jaundice, dark urine, unusual tiredness, or loss of seizure control. May cause thrombocytopenia/bleeding and hyperammonemia; periodic liver function tests and blood counts may be needed. Use caution in patients with liver disease, urea cycle disorders, or mitochondrial disorders. May impair alertness—avoid driving/operating machinery until you know its effect. Do not stop suddenly without medical advice.

Do not take Valrate CR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Valproate-containing medicines are contraindicated in pregnancy for epilepsy unless no alternative exists, and in all women of childbearing potential without a pregnancy prevention programme. Several are not suitable in significant liver disease.

Interactions with other medicines

Carbamazepine, phenytoin, phenobarbital/primidone, lamotrigine (increased risk of serious rash), topiramate (hyperammonemia), aspirin/salicylates (increased valproate levels/bleeding risk), warfarin/anticoagulants (bleeding risk), benzodiazepines and other CNS depressants (increased sedation), rifampicin (reduced levels)

How to store Valrate CR 300

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Valrate CR 300

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Valpo 200 mg/87 mg Tablet CR for treatment and prevention of seizures.</li> <li>Take it at the same time every day to maintain consistent levels in your body.</li> <li>Do not drive or do anything that requires mental focus until you know how Valpo 200 mg/87 mg Tablet CR affects you.</li> <li>Avoid consuming alcohol when taking Valpo 200 mg/87 mg Tablet CR, as it may cause excessive sleepiness or drowsiness.</li> <li>Monitor your weight during the treatment as Valpo 200 mg/87 mg Tablet CR can cause weight gain.</li> <li>Your doctor may monitor Valpo 200 mg/87 mg Tablet CR level, blood counts and liver function regularly throughout your treatment.  Inform your doctor if you develop fever, stomach pain, nausea or yellowing of your eyes or skin.</li> <li>Do not take Valpo 200 mg/87 mg Tablet CR if you are pregnant or planning to conceive or breastfeeding.</li> <li>Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:

IPCA LABORATORIES LTD`

Therapeutic class:

Antiepileptic

Drug class:

Anticonvulsant (Valproate; GABA-enhancing agent)