Actibile 150MG Tab
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
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Prescription required
Prescription requiredZydus Healthcare PharmaAntidepressant / Anxiolytic
Xet CR 12.5 Tablet
Clonazepam (0.25mg) + Paroxetine (12.5mg)
Available at our pharmacy counter
This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹261
Xet CR 12.5 Tablet is used for treatment of depression, generalized anxiety disorder (GAD), panic disorder, social anxiety disorder (social phobia), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Clonazepam (0.25mg) + Paroxetine (12.5mg)
Available variants: tablet 0.25mg + 12.5mg 10`S
Best price: ₹261 (₹26.11 per tablet)
MRP: ₹275
Prescription: Required
Manufacturer: ZYDUS HEALTHCARE PHARMA
Ordering notes
This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Xet CR 12.5 Tablet
Xet CR 12.5 Tablet contains Clonazepam (0.25mg) + Paroxetine (12.5mg). It belongs to the SSRI (Selective Serotonin Reuptake Inhibitor) class of medicines.
Uses of Xet CR 12.5 Tablet
- Treatment of depression
- generalized anxiety disorder (GAD)
- panic disorder
- social anxiety disorder (social phobia)
- obsessive-compulsive disorder (OCD)
- post-traumatic stress disorder (PTSD)
- premenstrual dysphoric disorder (PMDD)
Key benefits
- Helps relieve symptoms of depression
- Reduces anxiety and excessive worry (GAD)
- Decreases frequency/intensity of panic attacks
- Improves obsessive thoughts/compulsions in OCD
- Helps manage social anxiety symptoms
How Xet CR 12.5 Tablet works
Paroxetine is a selective serotonin reuptake inhibitor (SSRI). It increases serotonin levels in the brain by inhibiting its reuptake in nerve synapses, helping improve mood and reduce anxiety and panic symptoms.
How to take Xet CR 12.5 Tablet
Oral tablet (controlled-release). Take exactly as prescribed, usually once daily, preferably in the morning; can be taken with or without food. Swallow whole—do not crush, break, or chew. Do not stop suddenly without medical advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause deep unconsciousness and dangerously slow breathing, particularly with alcohol or an opioid. It can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Xet CR 12.5 Tablet
Most side effects of Xet CR are mild and settle as the body adjusts. Reported side effects include:
- Nausea
- dry mouth
- dizziness
- headache
- sleepiness
- insomnia
- sweating
- constipation
- diarrhea
- decreased appetite
- tremor
- sexual dysfunction
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Xet CR 12.5 Tablet
| Pregnancy | Use with caution / Consult doctor (may be associated with fetal risks; do not use unless clearly needed) |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | Use with caution (may increase drowsiness and impair judgment) |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Warnings and precautions
Prescription-only antidepressant. Risk of worsening depression or suicidal thoughts, especially in young adults—monitor closely. Do not stop abruptly (withdrawal symptoms). May cause serotonin syndrome (agitation, fever, sweating, diarrhea) especially with other serotonergic drugs. Can increase bleeding risk (with NSAIDs/anticoagulants). Use caution in seizure disorder, bipolar disorder (risk of mania), glaucoma (may precipitate angle-closure), liver/kidney impairment, and elderly (hyponatremia/SIADH). May impair driving due to drowsiness/dizziness.
Do not take Xet CR if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe breathing problems, sleep apnoea, or severe liver disease. Not for anyone with a history of dependence, except under specialist supervision. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Interactions with other medicines
MAO inhibitors/linezolid/methylene blue (contraindicated—serotonin syndrome), other serotonergic drugs (triptans, tramadol, lithium, St John’s wort), anticoagulants/antiplatelets/NSAIDs (bleeding risk), other CNS depressants (increased drowsiness), CYP2D6 substrates such as tricyclic antidepressants/antipsychotics and some beta-blockers (may increase their levels), tamoxifen (reduced activation/effect), alcohol (additive CNS effects)
How to store Xet CR 12.5 Tablet
Store at room temperature (below 25°C), in a dry place away from moisture and direct light. Keep in original blister pack and out of reach of children.
Expert advice for Xet CR 12.5 Tablet
Use it for the shortest course, and ask your doctor about talking therapy and sleep routine, which work without dependence. Take it only at bedtime if it is for sleep, and allow a full night before driving. Never share these medicines, and keep them secured. Give it a fair trial of several weeks, and keep your review appointments. Take it at the same time each day — at night if it makes you drowsy, in the morning if it disturbs sleep. Talking therapy alongside medicine works better than either alone for most people.
Manufacturer and class
- Manufacturer:
- ZYDUS HEALTHCARE PHARMA
- Therapeutic class:
- Antidepressant / Anxiolytic
- Drug class:
- SSRI (Selective Serotonin Reuptake Inhibitor)
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Xet CR 12.5 Tablet FAQs
What is Xet CR 12.5 Tablet used for?
Xet CR 12.5 Tablet is commonly used for Treatment of depression, generalized anxiety disorder (GAD), panic disorder, social anxiety disorder (social phobia), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Xet CR 12.5 Tablet?
Xet CR 12.5 Tablet contains Clonazepam (0.25mg) + Paroxetine (12.5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Xet CR 12.5 Tablet?
Oral tablet (controlled-release). Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Xet CR 12.5 Tablet work?
Paroxetine is a selective serotonin reuptake inhibitor (SSRI).
Is Xet CR 12.5 Tablet a prescription medicine?
Yes. Xet CR 12.5 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Xet CR 12.5 Tablet?
The side effects reported most often with Xet CR are Nausea, dry mouth, dizziness, headache, sleepiness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Xet CR 12.5 Tablet be taken during pregnancy?
Use with caution / Consult doctor (may be associated with fetal risks; do not use unless clearly needed) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Xet CR.
Can I drink alcohol while taking Xet CR 12.5 Tablet?
Use with caution (may increase drowsiness and impair judgment)
What if I miss a dose of Xet CR 12.5 Tablet?
Take it as soon as you remember.
Is Xet CR 12.5 Tablet habit forming?
No. Xet CR 12.5 Tablet is not known to be habit forming when taken as prescribed.
How much does Xet CR 12.5 Tablet cost on PingMeDoc Pharmacy?
Xet CR 12.5 Tablet starts at ₹261 (MRP ₹275) on PingMeDoc Pharmacy. Available in tablet 0.25mg + 12.5mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Xet CR 12.5 Tablet?
Xet CR 12.5 Tablet is manufactured by ZYDUS HEALTHCARE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Xet CR 12.5 Tablet delivered?
Xet CR 12.5 Tablet is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.
Xet CR 12.5 Tablet, Quick facts
- Salt
- Clonazepam (0.25mg) + Paroxetine (12.5mg)
- Form
- tablet
- Best price
- ₹261 (₹26.11 per tablet)
- MRP
- ₹275
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- ZYDUS HEALTHCARE PHARMA
- Manufacturer
- ZYDUS HEALTHCARE PHARMA
- Therapeutic class
- Antidepressant / Anxiolytic
- Drug class
- SSRI (Selective Serotonin Reuptake Inhibitor)
- Habit forming
- No
- Variants
- tablet 0.25mg + 12.5mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- Manufacturer labeling
- CDSCO regulatory framework, established medical literature (SSRIs/paroxetine), standard pharmacology references
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Xet CR 12.5 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.