Zerodol Pg 200/75

Composition of Zerodol Pg 200/75

Zerodol Pg 200/75 contains Aceclofenac (200mg) + Pregabalin (75mg). It belongs to the NSAID (aceclofenac) + Gabapentinoid anticonvulsant (pregabalin) class of medicines.

Uses of Zerodol Pg 200/75

• Relief of pain associated with nerve involvement and inflammation such as neuropathic pain
• sciatica/radiculopathy
• low back pain with radiating pain
• musculoskeletal pain where analgesic plus neuropathic pain control is needed.

Key benefits

• Relieves inflammatory pain
• Reduces nerve pain symptoms (burning/tingling)
• Improves mobility and function
• Helpful in sciatica/radiculopathy-related pain

How Zerodol Pg 200/75 works

Aceclofenac is an NSAID that reduces pain and inflammation by inhibiting COX enzymes and lowering prostaglandin production. Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS, reducing release of excitatory neurotransmitters and thereby decreasing nerve pain.

How to take Zerodol Pg 200/75

Take as prescribed by the doctor. Usually taken orally once daily after food (SR aceclofenac) with water; swallow whole and do not crush/chew. Avoid driving if you feel drowsy; do not stop pregabalin suddenly without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Zerodol-PG 200/75 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zerodol Pg 200/75

Most side effects of Zerodol Pg 200/75 are mild and settle as the body adjusts. Reported side effects include:

• Dizziness
• drowsiness
• blurred vision
• peripheral edema (swelling)
• dry mouth
• nausea
• gastritis/heartburn
• constipation
• weight gain
• headache

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zerodol Pg 200/75

Warnings and precautions

Prescription medicine. NSAID-related risks: stomach ulcer/bleeding, kidney injury, and fluid retention; use caution in elderly, those with peptic ulcer history, kidney/liver disease, heart failure, or uncontrolled hypertension. Pregabalin may cause dizziness/somnolence and can increase risk of falls; caution with driving/operating machinery. Do not discontinue abruptly (withdrawal symptoms possible). Seek urgent care for severe abdominal pain/black stools, breathing difficulty, facial swelling/rash, or suicidal thoughts/mood changes.

Do not take Zerodol Pg 200/75 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Alcohol and other CNS depressants (increased sedation), opioids/benzodiazepines (respiratory/CNS depression risk), antihypertensives/diuretics (reduced effect and kidney risk with NSAIDs), anticoagulants/antiplatelets like warfarin/aspirin/clopidogrel (bleeding risk), other NSAIDs/corticosteroids (GI bleed risk), ACE inhibitors/ARBs (renal risk), lithium (increased levels), methotrexate (toxicity risk)

How to store Zerodol Pg 200/75

Store below 25°C in a cool, dry place away from moisture and light. Keep in original pack and out of reach of children.

Expert advice for Zerodol Pg 200/75

Zerodol-PG 200/75 Tablet SR is used to treat neuropathic or nerve pain. Take it as per dose and duration suggested by your doctor. Take it with food to avoid getting stomach upset. It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration. Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment. Do not stop taking medicine without talking to your doctor. Take it as per dose and duration suggested by your doctor. Take it with food to avoid getting stomach upset. It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration. Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment. Do not stop taking medicine without talking to your doctor.

Manufacturer and class

Manufacturer:

IPCA LABORATORIES LTD`

Therapeutic class:

Analgesic (Pain relief) / Anti-inflammatory; Neuropathic pain agent

Drug class:

NSAID (aceclofenac) + Gabapentinoid anticonvulsant (pregabalin)