Zidliv 150 mg Tablet

Composition of Zidliv 150 mg Tablet

Zidliv 150 mg Tablet contains Zidovudine 150 mg (as Zidovudine) tablet. It belongs to the Nucleoside Reverse Transcriptase Inhibitor (NRTI) class of medicines.

Uses of Zidliv 150 mg Tablet

Treatment of HIV-1 infection as part of combination antiretroviral therapy (ART); prevention of mother-to-child transmission of HIV (as per specialist regimen/guidelines).

Key benefits

• Reduces HIV viral replication
• Helps increase/maintain CD4 count
• Lowers risk of HIV-related infections when used with ART
• Used in regimens for prevention of mother-to-child transmission
• Helps achieve/maintain viral suppression with combination therapy

How Zidliv 150 mg Tablet works

Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI). It is converted inside cells to an active triphosphate form that inhibits HIV reverse transcriptase and causes chain termination, reducing viral replication.

How to take Zidliv 150 mg Tablet

Tablet for oral use. Take exactly as prescribed, usually in combination with other antiretroviral medicines; may be taken with or without food. Take at the same time each day and do not stop without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause confusion, kidney injury and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zidliv 150 mg Tablet

Most side effects of Zidliv are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• headache
• diarrhea
• abdominal pain
• fatigue
• anemia
• neutropenia
• fever
• muscle pain
• insomnia
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zidliv 150 mg Tablet

Warnings and precautions

Use only under supervision of an HIV specialist and always as part of combination therapy. May cause bone marrow suppression (anemia, neutropenia); regular CBC monitoring required. Risk of lactic acidosis and severe hepatomegaly with steatosis; seek urgent care for persistent nausea/vomiting, abdominal pain, deep rapid breathing, or severe weakness. Use caution in liver disease and in patients with pre-existing anemia/neutropenia. Long-term use may be associated with myopathy and lipoatrophy. Do not share needles; continue safe sex practices as this medicine reduces viral load but does not cure HIV.

Do not take Zidliv if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Other myelosuppressive drugs (e.g., ganciclovir, interferon alfa, ribavirin) may increase risk of anemia/neutropenia; probenecid may increase zidovudine levels; valproate may increase zidovudine exposure; rifampicin may reduce zidovudine concentrations; avoid/stay cautious with other nephrotoxic/hepatotoxic medicines; do not co-administer with stavudine (antagonistic effect).

How to store Zidliv 150 mg Tablet

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Expert advice for Zidliv 150 mg Tablet

Start as early as your doctor advises. Keep well hydrated through the course.

Manufacturer and class

Manufacturer:

FDC LIMITED

Therapeutic class:

Antiviral (Antiretroviral)

Drug class:

Nucleoside Reverse Transcriptase Inhibitor (NRTI)