Zifi X 1 g Injection

Composition of Zifi X 1 g Injection

Zifi X 1 g Injection contains Cefixime 1 g (as cefixime trihydrate) powder for injection. It belongs to the Third-generation cephalosporin (beta-lactam antibiotic) class of medicines.

Uses of Zifi X 1 g Injection

• Treatment of susceptible bacterial infections such as lower respiratory tract infections (e.g.
• pneumonia/bronchitis)
• urinary tract infections
• enteric fever (typhoid)
• otitis media
• sinusitis
• and other systemic infections as per culture sensitivity

Key benefits

• Treats susceptible bacterial infections
• Effective in respiratory tract infections
• Useful in urinary tract infections
• Used in enteric fever (typhoid) as prescribed
• Broad-spectrum cephalosporin coverage

How Zifi X 1 g Injection works

Cefixime is a third-generation cephalosporin antibiotic. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death of susceptible bacteria.

How to take Zifi X 1 g Injection

Take exactly as prescribed by your doctor.

Side effects of Zifi X 1 g Injection

Most side effects of Zifi X are mild and settle as the body adjusts. Reported side effects include:

• Diarrhoea
• nausea
• vomiting
• abdominal pain
• indigestion
• headache
• dizziness
• rash
• itching
• injection-site pain/redness
• transient rise in liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zifi X 1 g Injection

Warnings and precautions

Prescription-only antibiotic. Do not use in patients with known hypersensitivity to cefixime/cephalosporins; use caution in penicillin allergy. Adjust dose in renal impairment. May cause antibiotic-associated diarrhoea/Clostridioides difficile colitis; seek care if severe watery/bloody diarrhoea occurs. Use caution in history of colitis. Prolonged use may cause superinfection. Monitor for serious allergic reactions (anaphylaxis), severe skin reactions, and blood dyscrasias though rare.

Do not take Zifi X if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to cephalosporin antibiotics.

Interactions with other medicines

Warfarin/other anticoagulants (may increase bleeding risk/INR), probenecid (may increase cefixime levels), live oral typhoid vaccine (reduced vaccine effect), antacids containing magnesium/aluminium (may reduce absorption—relevant mainly for oral forms), nephrotoxic drugs like aminoglycosides/loop diuretics (use caution, especially in renal impairment)

How to store Zifi X 1 g Injection

Store below 25°C, protect from light and moisture. After reconstitution, use immediately or within the time limits specified on the label; do not freeze reconstituted solution.

Expert advice for Zifi X 1 g Injection

Space the doses evenly and complete the course. Keep the reconstituted syrup as the pharmacist instructed and discard it after the stated number of days.

Manufacturer and class

Manufacturer:

FDC LIMITED

Therapeutic class:

Antibiotic

Drug class:

Third-generation cephalosporin (beta-lactam antibiotic)