Zithrox XL 100 Suspension

Composition of Zithrox XL 100 Suspension

Zithrox XL 100 Suspension contains Azithromycin 100 mg/5 mL (as azithromycin dihydrate) oral suspension. It belongs to the Macrolide antibiotic class of medicines.

Uses of Zithrox XL 100 Suspension

• Treatment of susceptible bacterial infections such as acute otitis media
• acute bacterial sinusitis
• pharyngitis/tonsillitis
• community-acquired pneumonia
• acute bronchitis exacerbations
• and skin/soft tissue infections (as prescribed).

Key benefits

• Treats susceptible bacterial respiratory infections
• Helps in ear infections (otitis media)
• Useful in throat infections (tonsillitis/pharyngitis)
• Effective in certain skin and soft tissue infections
• Once-daily dosing in many regimens

How Zithrox XL 100 Suspension works

Azithromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. This stops growth of susceptible bacteria and helps clear the infection.

How to take Zithrox XL 100 Suspension

Oral suspension. Reconstitute with boiled and cooled water up to the mark; shake well before each dose. Give the dose exactly as prescribed (often once daily), with or without food (give after food if stomach upset). Use a measuring syringe/cup; complete the full course.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, hearing disturbance and heart rhythm changes. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zithrox XL 100 Suspension

Most side effects of Zithrox XL are mild and settle as the body adjusts. Reported side effects include:

• Diarrhoea
• nausea
• vomiting
• abdominal pain
• indigestion
• headache
• dizziness
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zithrox XL 100 Suspension

Warnings and precautions

Use only for bacterial infections (not viral). Inform doctor if history of allergy to azithromycin/erythromycin/macrolides, liver disease, jaundice with prior antibiotic use, myasthenia gravis, or heart rhythm problems (QT prolongation). Seek urgent care for severe diarrhoea, allergic reactions, or signs of liver injury (yellow eyes/skin, dark urine). Dose adjustment/monitoring may be needed in hepatic impairment.

Do not take Zithrox XL if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to macrolide antibiotics, or with certain heart rhythm disorders.

Interactions with other medicines

Antacids containing aluminium/magnesium (separate dosing), warfarin/other anticoagulants (bleeding risk/INR monitoring), digoxin (increased levels), cyclosporine, antiarrhythmics/QT-prolonging drugs (e.g., amiodarone, sotalol, quinolones, some antipsychotics), ergot derivatives (avoid), statins (rare myopathy risk)

How to store Zithrox XL 100 Suspension

Store dry powder at room temperature away from moisture and light. After reconstitution, store as per label (commonly below 25°C; do not freeze) and use within the advised period; keep bottle tightly closed and shake well before use.

Expert advice for Zithrox XL 100 Suspension

Take it at the same time each day and complete the course. Taking it with food reduces nausea unless the pack says to take it on an empty stomach.

Manufacturer and class

Manufacturer:

MACLEODS PHARMACEUTICALS LTD

Therapeutic class:

Antibiotic

Drug class:

Macrolide antibiotic