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Prescription requiredEast West PharmaAnxiolytic and hypnotic

Zolpirest M

Zolpidem (10mg) + Melatonin (3mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹120

Zolpirest M is used for this medicine is used in the treatment of anxiety, insomnia, panic disorder, seizures and muscle spasm.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Zolpidem (10mg) + Melatonin (3mg)
Available variants: NA 10`S
Best price: ₹120
MRP: ₹127
Prescription: Required
Manufacturer: EAST WEST PHARMA

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Zolpirest M

Zolpirest M contains Zolpidem (10mg) + Melatonin (3mg). It belongs to the Benzodiazepine / sedative-hypnotic class of medicines.

Uses of Zolpirest M

  • This medicine is used in the treatment of anxiety
  • insomnia
  • panic disorder
  • seizures and muscle spasm.

Key benefits

  • Rapid relief of severe anxiety
  • Short-term help with sleep
  • Controls acute seizures

How Zolpirest M works

Zolpirest-M Tablet is a combination of two medicines: Melatonin and Zolpidem which work on your brain to make you feel relaxed and sleepy. Melatonin is a natural hormone which regulates the sleep-wake cycle and helps fall asleep. Zolpidem is a sedative which works by slowing activity of the nerve cells in the brain and helps sleep for longer.

How to take Zolpirest M

Take exactly as prescribed by your doctor.

Side effects of Zolpirest M

Most side effects of Zolpirest M are mild and settle as the body adjusts. Reported side effects include:

  • Drowsiness
  • Dizziness
  • Unsteadiness
  • Poor concentration
  • Memory lapses
  • Dry mouth

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zolpirest M

PregnancyZolnik-M Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingZolmap-M 10 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.Zolmap-M 10 Tablet is safe as per American Association of Pregnancy.
AlcoholIt is unsafe to consume alcohol with Zolmap-M 10 Tablet.
DrivingDo not drive or operate machinery while taking this medicine.
KidneyThere is limited information available on the use of Zolmap-M 10 Tablet in patients with kidney disease. Please consult your doctor.However, based on the limited information available it is advised that Zolmap-M 10 Tablet should be used with caution in patients with kidney disease.
LiverZolmap-M 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zolmap-M 10 Tablet may be needed. Please consult your doctor.Zolmap-M 10 Tablet is generally started at a low dose in patients with mild to moderate liver disease and is not recommended in patients with severe liver disease.
Habit formingYes

Warnings and precautions

These medicines cause dependence. They are intended for the shortest possible course — usually two to four weeks — and are not a long-term treatment for anxiety or sleeplessness. Never stop a regular course suddenly. Withdrawal can cause severe anxiety, tremor and fits. Your doctor will taper it slowly. Do not drive or operate machinery. Drowsiness and slowed reactions can continue into the next day. Never combine with alcohol or with opioid painkillers — together they can stop your breathing. Older people are far more likely to fall, become confused or have memory problems on these medicines. Several of these are Schedule H1 medicines and must be dispensed against a prescription and entered in the pharmacy register.

Do not take Zolpirest M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe breathing problems, sleep apnoea, or severe liver disease. Not for anyone with a history of dependence, except under specialist supervision.

Interactions with other medicines

Alcohol, opioids, antihistamines, muscle relaxants and other sedatives all deepen the sedation, sometimes fatally.

How to store Zolpirest M

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Zolpirest M

Use it for the shortest course, and ask your doctor about talking therapy and sleep routine, which work without dependence. Take it only at bedtime if it is for sleep, and allow a full night before driving. Never share these medicines, and keep them secured.

Manufacturer and class

Manufacturer:
EAST WEST PHARMA
Therapeutic class:
Anxiolytic and hypnotic
Drug class:
Benzodiazepine / sedative-hypnotic

Substitutes for Zolpirest M

Medicines with the same active ingredient (Zolpidem (10mg) + Melatonin (3mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Zolpirest M
Cirq Plus 5 mg TabletERIS LIFE SCIENCES PVT LTDtablet · 10`S₹8628% cheaper
Zolsoma 10 mg TabletCIPLA LIMITEDtablet · 10`S₹14016% more
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Zolpirest M FAQs

What is Zolpirest M used for?
Zolpirest M is commonly used for This medicine is used in the treatment of anxiety, insomnia, panic disorder, seizures and muscle spasm. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zolpirest M?
Zolpirest M contains Zolpidem (10mg) + Melatonin (3mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How does Zolpirest M work?
Zolpirest-M Tablet is a combination of two medicines: Melatonin and Zolpidem which work on your brain to make you feel relaxed and sleepy.
Is Zolpirest M a prescription medicine?
Yes. Zolpirest M is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zolpirest M?
The side effects reported most often with Zolpirest M are Drowsiness, Dizziness, Unsteadiness, Poor concentration, Memory lapses. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zolpirest M be taken during pregnancy?
Zolnik-M Tablet may be unsafe to use during pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zolpirest M.
Can I drink alcohol while taking Zolpirest M?
It is unsafe to consume alcohol with Zolmap-M 10 Tablet.
Is Zolpirest M habit forming?
Yes Take Zolpirest M only as directed and for the duration your doctor advises.
Is there a cheaper substitute for Zolpirest M?
Cirq Plus 5 mg Tablet has the same active ingredient and strength and is listed from ₹86 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Zolpirest M cost on PingMeDoc Pharmacy?
Zolpirest M starts at ₹120 (MRP ₹127) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zolpirest M?
Zolpirest M is manufactured by EAST WEST PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zolpirest M delivered?
Zolpirest M is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Zolpirest M, Quick facts

Salt
Zolpidem (10mg) + Melatonin (3mg)
Best price
₹120
MRP
₹127
Prescription
Required (Rx)
Schedule
Schedule H1
Brand
EAST WEST PHARMA
Manufacturer
EAST WEST PHARMA
Therapeutic class
Anxiolytic and hypnotic
Drug class
Benzodiazepine / sedative-hypnotic
Habit forming
Yes
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Zolpirest M.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.