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Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Sulbactam (500mg) + Cefoperazone (1000mg)
Zonamax ES 1000 mg/500 mg Injection is used in the treatment of bacterial infections.
Zonamax ES 1000 mg/500 mg Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.
Take exactly as prescribed by your doctor.
Common side effects of Zonamax Es may include:

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