
Abione Tab
Intas Pharmaceuticals Ltd - Tablet - 250mg - 10 S
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Zoryl M3 Forte Tablet is used for type 2 diabetes mellitus when diet and exercise alone are insufficient; helps control high blood sugar in adults.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Type 2 diabetes mellitus when diet and exercise alone are insufficient; helps control high blood sugar in adults
Glimepiride (a sulfonylurea) increases insulin release from the pancreas and improves insulin sensitivity. Metformin reduces glucose production in the liver and decreases intestinal glucose absorption, improving peripheral glucose uptake. Together they lower fasting and post‑meal blood glucose.
Oral tablet. Take exactly as prescribed, usually once daily with food (preferably with the main meal) to reduce stomach upset and risk of low sugar. Swallow whole; do not crush or chew if it is a prolonged/extended-release tablet. Monitor blood glucose regularly.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Zoryl M2 Forte Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Zoryl M3 Forte than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Zoryl M3 Forte are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended / Consult doctor |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Avoid |
| Driving | Driving CAUTION |
| Kidney | Kidney UNSAFE |
| Liver | Liver UNSAFE |
| Habit forming | No |
Risk of hypoglycaemia (more likely with missed meals, excess exercise, alcohol, elderly, renal/hepatic impairment). Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, abdominal pain, or unusual sleepiness. Use with caution in kidney or liver disease; periodic renal function monitoring is required. Temporarily stop metformin before/at iodinated contrast procedures and during major surgery as advised by doctor. Not for type 1 diabetes or diabetic ketoacidosis.
Alcohol, insulin and other antidiabetics (increased hypoglycaemia), beta-blockers (may mask hypoglycaemia), ACE inhibitors (may enhance glucose-lowering), corticosteroids and diuretics (may raise glucose), rifampicin (reduces effect of glimepiride), azole antifungals/macrolides (increase hypoglycaemia risk), iodinated contrast media (increases lactic acidosis risk with metformin), cimetidine (increases metformin levels)
Store below 25°C in a dry place, protected from light and moisture. Keep in original pack and out of reach of children.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Zoryl M2 Forte Tablet PR. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Zoryl M2 Forte Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

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The information on Zoryl M3 Forte Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.