
Augmentin 1000MG Duo
Glaxo Smithkline Pharma - 1000 mg - 10 S
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Ibuprofen (400mg) + Paracetamol (325mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Zupar Tablet is used for pain relief Treatment of Fever.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Zupar Tablet contains Ibuprofen (400mg) + Paracetamol (325mg). It belongs to the Non-steroidal anti-inflammatory drug and Para-aminophenol derivative class of medicines.
Pain relief Treatment of Fever
Zupar 400mg/325mg Tablet is a combination of two medicines: Ibuprofen and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zupar 400mg/325mg Tablet should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Zupar 400mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Zupar are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy UNSAFE |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving UNSAFE |
| Kidney | Kidney UNSAFE |
| Liver | Liver UNSAFE |
| Habit forming | No |
Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with severe liver disease, except under medical supervision.
Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
You have been prescribed this combination medicine to relieve pain, inflammation, and fever. Take it with food to avoid getting an upset stomach. Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to stomach bleeding and kidney problems. Avoid consuming alcohol when taking Zupar 400mg/325mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage. Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough and cold) without asking your doctor first.
Medicines with the same active ingredient (Ibuprofen (400mg) + Paracetamol (325mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Zupar Tablet |
|---|---|---|---|
| Brustan Tablet | 1X10 | ₹14 | 113% more |
| Brustan 60 ml Suspension | 60ML | ₹27 | 304% more |
| Alkemflam Tablet | 1X20 | ₹31 | 376% more |
| Ibugesic Plus TabletCIPLA LIMITED | tablet · 20 Tablet | ₹37 | 468% more |
| Combiflam TabletSANOFI INDIA LTD | tablet · 20 Tablet | ₹52 | 686% more |
| Ibuflam Tablet | 1X10 | ₹67 | 911% more |

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.