
Actibile 150MG Tab
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
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Prescription required
Pyrazinamide (1000mg)
Zypara 1000 SR Tablet is used for fever, mild to moderate pain such as headache, toothache, body ache, musculoskeletal pain, back pain, and pain associated with cold/flu.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Zypara 1000 SR Tablet contains Pyrazinamide (1000mg). It belongs to the Non-opioid analgesic (para-aminophenol derivative) class of medicines.
Paracetamol reduces the production of prostaglandins in the central nervous system, which lowers pain perception and helps reduce fever by acting on the brain’s temperature-regulating center. The sustained-release formulation provides prolonged symptom relief.
Take exactly as prescribed by your doctor.
Most side effects of Zypara are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Breast feeding SAFE IF PRESCRIBED |
| Alcohol | Avoid |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Do not exceed the recommended total daily dose of paracetamol from all products. Risk of serious liver damage with overdose, chronic alcohol use, or pre-existing liver disease. Use with caution in liver impairment, chronic malnutrition, dehydration, or severe kidney disease. Stop and seek medical help if allergic reactions (rash, swelling, breathing difficulty) or signs of liver injury (persistent nausea, dark urine, jaundice) occur. Not for prolonged self-use without medical advice.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will adjust or change the regimen in significant liver disease.
Alcohol, warfarin/coumarin anticoagulants (with prolonged regular use may increase bleeding risk), enzyme inducers (carbamazepine, phenytoin, phenobarbital, rifampicin, isoniazid) increasing hepatotoxicity risk, probenecid (may increase paracetamol levels), cholestyramine (reduces absorption if taken together)
Store below 25°C in a dry place, protected from moisture and direct light. Keep out of reach of children.
Zypara 1000mg Tablet SR along with other medications effectively treats tuberculosis. Do not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects. Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. Avoid drinking alcohol while taking Zypara 1000mg Tablet SR as this may increase the risk of side effects on the liver. Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Zypara 1000mg Tablet SR as it may make hormonal contraceptives such as the pill less effective.

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The information on Zypara 1000 SR Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.