Advastat 20MG Tab

Tablet

High cholesterol (hypercholesterolaemia), mixed dyslipidaemia, high triglycerides; prevention of cardiovascular events (heart attack, stroke) in high-risk patients

Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis in the liver. This lowers LDL (bad cholesterol) and triglycerides and can modestly raise HDL (good cholesterol), reducing plaque formation and cardiovascular risk.

Tablet for oral use. Take exactly as prescribed, usually once daily at the same time each day, with or without food. Continue diet and exercise advised by the doctor; do not stop without medical advice.

Headache, nausea, diarrhoea, constipation, abdominal pain, indigestion, muscle pain, joint pain, weakness, increased liver enzymes

Prescription medicine. Risk of muscle injury (myopathy/rhabdomyolysis)—seek medical help for unexplained muscle pain/weakness, especially with fever or dark urine. Liver function may be affected; monitoring may be needed and avoid use in active liver disease. Not recommended in pregnancy and breastfeeding. Use caution in elderly, kidney problems, hypothyroidism, heavy alcohol use, and history of muscle disorders. Avoid large quantities of grapefruit juice.

Strong CYP3A4 inhibitors (clarithromycin, erythromycin, ketoconazole/itraconazole, protease inhibitors), cyclosporine, gemfibrozil/other fibrates, niacin, colchicine, amiodarone, verapamil/diltiazem, warfarin (monitor INR), digoxin, ezetimibe, grapefruit juice

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

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