Amcard 5MG Tab

Tablet

Treatment of hypertension (high blood pressure); treatment of chronic stable angina and vasospastic (Prinzmetal) angina; may help reduce risk of cardiovascular events related to high blood pressure.

Amlodipine is a dihydropyridine calcium channel blocker. It relaxes and widens blood vessels by blocking calcium entry into vascular smooth muscle, lowering blood pressure and improving blood flow to the heart to reduce angina symptoms.

Tablet for oral use. Take as prescribed by the doctor, usually once daily at the same time each day, with or without food. Swallow with water; do not stop suddenly without medical advice.

Headache,dizziness,flushing,ankle/feet swelling (peripheral edema),palpitations,fatigue,nausea,abdominal pain,somnolence

Use with caution in liver disease (dose adjustment may be needed). May cause dizziness—avoid driving/operating machinery until you know the effect. Monitor for swelling of ankles/feet and low blood pressure symptoms (lightheadedness, fainting). Use cautiously in severe aortic stenosis, heart failure, or very low blood pressure. Do not discontinue without consulting your doctor.

Other antihypertensives (additive BP lowering),CYP3A4 inhibitors (e.g., clarithromycin, azole antifungals, ritonavir) may increase amlodipine levels,CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin) may reduce effect,Simvastatin (limit simvastatin dose; increased simvastatin exposure),Grapefruit juice (may increase levels in some patients)

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

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