Dydrofem Tab

Tablet

Treatment of progesterone deficiency states such as irregular/abnormal uterine bleeding (DUB), secondary amenorrhoea, dysmenorrhoea, endometriosis, premenstrual syndrome (PMS), luteal phase support and infertility due to luteal insufficiency; support in threatened/recurrent miscarriage due to luteal insufficiency; part of hormone replacement therapy (HRT) with estrogen to prevent endometrial hyperplasia.

Dydrogesterone is a synthetic progestogen that mimics the action of natural progesterone. It transforms the proliferative endometrium into a secretory endometrium, stabilizes the uterine lining and helps regulate the menstrual cycle and support pregnancy in progesterone-deficient states.

Tablet for oral use. Take exactly as prescribed; dose and days of cycle depend on the condition (often taken in the luteal phase). Can be taken with or without food; take at the same time each day. If a dose is missed, take it as soon as remembered unless it is near the next dose—do not double dose.

Headache, nausea, abdominal pain/bloating, breast tenderness, dizziness, fatigue, spotting/breakthrough bleeding, mood changes

Use only under medical supervision. Rule out pregnancy/ectopic pregnancy and malignancy before treating abnormal uterine bleeding. Use with caution in liver disease, history of depression, thromboembolic disorders, or porphyria; stop and seek care for jaundice, severe headache/vision changes, chest pain, breathlessness, leg swelling/pain, or allergic reaction. May cause dizziness—avoid driving if affected. Not a contraceptive. In HRT, should be used with estrogen as directed; risk-benefit assessment is needed for long-term use.

Enzyme inducers may reduce effect (e.g., rifampicin, rifabutin, carbamazepine, phenytoin, phenobarbital, primidone, topiramate, St John’s wort). Some antivirals and other strong CYP modulators may alter levels; consult doctor with any new medicine.

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Duphaston 10 mg Tablet, Dydrolin 10 mg Tablet, Dydropil 10 mg Tablet, Dydrogesterone 10 mg Tablet (generic), Dydrosure 10 mg Tablet