Rosvie Cv 20MG Cap

Capsule

Prevention of heart attack and stroke in patients at risk; management of atherosclerotic cardiovascular disease, especially when antiplatelet therapy and cholesterol lowering are both required (e.g., after acute coronary syndrome/angioplasty/stent, established coronary artery disease).

Rosuvastatin is a statin (HMG‑CoA reductase inhibitor) that reduces LDL cholesterol and triglycerides and helps stabilize plaque. Clopidogrel is an antiplatelet that irreversibly blocks the platelet P2Y12 (ADP) receptor, reducing platelet aggregation and preventing clot formation.

Take by mouth as advised by the doctor, usually once daily at the same time; can be taken with or without food. Swallow the capsule whole with water; do not crush or open. Do not stop clopidogrel abruptly without medical advice, especially after stent placement.

Bleeding, easy bruising, nosebleed, indigestion, abdominal pain, diarrhoea, headache, dizziness, muscle pain (myalgia), weakness, raised liver enzymes

Prescription medicine. Increased risk of bleeding (including GI or intracranial); seek urgent care for black stools, vomiting blood, unusual bruising or prolonged bleeding. Statin-related muscle injury (myopathy/rhabdomyolysis) risk—report unexplained muscle pain/weakness, especially with fever; caution in kidney disease and hypothyroidism. Monitor liver function; avoid in active liver disease. Use caution in elderly and in patients with history of peptic ulcer/bleeding. Inform doctor before surgery/dental procedures; clopidogrel may need temporary stoppage as advised. Not for use in children unless prescribed by specialist.

Other antiplatelets/anticoagulants (aspirin, warfarin, heparin, apixaban/rivaroxaban) and NSAIDs (ibuprofen, naproxen) increase bleeding risk; PPIs especially omeprazole/esomeprazole may reduce clopidogrel effect; strong CYP3A4 inhibitors/inducers may affect clopidogrel activation; rosuvastatin interactions with cyclosporine (contraindicated/avoid), gemfibrozil and other fibrates/niacin (↑myopathy risk), certain antivirals, and excessive alcohol (↑liver risk).

Store below 25°C in a cool, dry place; protect from moisture and direct light. Keep out of reach of children.

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