Temoside 100 mg Capsule

Take exactly as directed by the oncologist. Swallow the capsule whole with water on an empty stomach (typically 1 hour before or 2 hours after food), preferably at the same time each day; do not open, crush, or chew. Use anti-nausea medicine if prescribed; follow the treatment cycle schedule strictly.

Temozolomide is an alkylating agent that converts to an active metabolite (MTIC) in the body. It methylates DNA in tumor cells, leading to DNA damage and inhibition of cancer cell growth and replication.

Cytotoxic chemotherapy—use only under specialist supervision. Can cause severe myelosuppression (low blood counts) leading to infections/bleeding; regular CBC monitoring required. Risk of opportunistic infections (including Pneumocystis jirovecii pneumonia), especially with concomitant radiotherapy or steroids—prophylaxis may be needed. Avoid pregnancy; may harm the unborn baby. Men should use effective contraception during treatment and for a period after; fertility may be affected. Do not open capsules; avoid contact with powder (wash thoroughly if contact occurs). Seek urgent care for fever, sore throat, unusual bruising/bleeding, breathlessness, or severe rash.

Valproic acid (may alter temozolomide clearance), other myelosuppressive/chemotherapy agents (additive bone marrow suppression), corticosteroids and radiotherapy (increased infection risk), live vaccines (avoid during immunosuppression), drugs affecting kidney/liver function (monitoring advised)

Store below 25°C in original pack, protected from light and moisture. Keep out of reach of children. Handle as a cytotoxic medicine; follow disposal instructions from the hospital/pharmacy.

Temodal 100 mg Capsule, Temoz 100 mg Capsule, Temonat 100 mg Capsule, Temonide 100 mg Capsule, Temonat-100 Capsule