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Before you take it
Not recommended / Consult doctor
Breast feeding UNSAFE
Use with caution (may worsen dizziness, nausea and liver strain); best to avoid during chemotherapy
Driving UNSAFE
Kidney CAUTION
Liver CAUTION
Monograph
Capsule
Treatment of certain brain cancers such as glioblastoma multiforme (newly diagnosed and recurrent) and anaplastic astrocytoma, as prescribed by an oncologist.
Temozolomide is an alkylating agent that converts to an active metabolite (MTIC) in the body. It methylates DNA in tumor cells, leading to DNA damage and inhibition of cancer cell growth and replication.
Take exactly as directed by the oncologist. Swallow the capsule whole with water on an empty stomach (typically 1 hour before or 2 hours after food), preferably at the same time each day; do not open, crush, or chew. Use anti-nausea medicine if prescribed; follow the treatment cycle schedule strictly.
Nausea, vomiting, loss of appetite, fatigue, constipation, headache, hair loss, fever, low white blood cells (neutropenia/lymphopenia), low platelets (thrombocytopenia), anemia, rash
Cytotoxic chemotherapy—use only under specialist supervision. Can cause severe myelosuppression (low blood counts) leading to infections/bleeding; regular CBC monitoring required. Risk of opportunistic infections (including Pneumocystis jirovecii pneumonia), especially with concomitant radiotherapy or steroids—prophylaxis may be needed. Avoid pregnancy; may harm the unborn baby. Men should use effective contraception during treatment and for a period after; fertility may be affected. Do not open capsules; avoid contact with powder (wash thoroughly if contact occurs). Seek urgent care for fever, sore throat, unusual bruising/bleeding, breathlessness, or severe rash.
Valproic acid (may alter temozolomide clearance), other myelosuppressive/chemotherapy agents (additive bone marrow suppression), corticosteroids and radiotherapy (increased infection risk), live vaccines (avoid during immunosuppression), drugs affecting kidney/liver function (monitoring advised)
Store below 25°C in original pack, protected from light and moisture. Keep out of reach of children. Handle as a cytotoxic medicine; follow disposal instructions from the hospital/pharmacy.
Temodal 100 mg Capsule, Temoz 100 mg Capsule, Temonat 100 mg Capsule, Temonide 100 mg Capsule, Temonat-100 Capsule
At a glance
Good to know
Treatment of certain brain cancers such as glioblastoma multiforme (newly diagnosed and recurrent) and anaplastic astrocytoma, as prescribed by an oncologist.
Nausea, vomiting, loss of appetite, fatigue, constipation, headache, hair loss, fever, low white blood cells (neutropenia/lymphopenia), low platelets (thrombocytopenia), anemia, rash
Temozolomide is an alkylating agent that converts to an active metabolite (MTIC) in the body. It methylates DNA in tumor cells, leading to DNA damage and inhibition of cancer cell growth and replication.
Take exactly as directed by the oncologist. Swallow the capsule whole with water on an empty stomach (typically 1 hour before or 2 hours after food), preferably at the same time each day; do not open, crush, or chew. Use anti-nausea medicine if prescribed; follow the treatment cycle schedule strictly.
Store below 25°C in original pack, protected from light and moisture. Keep out of reach of children. Handle as a cytotoxic medicine; follow disposal instructions from the hospital/pharmacy.
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
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Brand
COMMON PRODUCTS
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Manufacturer: COMMON PRODUCTS
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling/package insert, established oncology literature (e.g., NCCN/ESMO guidance), US FDA/EMA monographs for temozolomide, Indian regulatory/market data (CDSCO where applicable)
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