Zonisep 100 10S

Zonisamide (100mg)

Treatment of epilepsy/seizure disorders (as adjunct therapy for partial-onset seizures); may be used for other seizure types as decided by the physician.

Zonisamide is an antiepileptic medicine that helps reduce abnormal electrical activity in the brain. It blocks voltage-gated sodium channels and T-type calcium channels and may enhance inhibitory neurotransmission, thereby lowering seizure frequency.

Take tablet/capsule exactly as prescribed by the doctor, usually once or twice daily. Can be taken with or without food; take at the same time each day and swallow whole with water. Do not stop suddenly; dose is usually titrated and tapered as advised.

dizziness, drowsiness, headache, nausea, loss of appetite, weight loss, fatigue, difficulty concentrating, irritability

Prescription-only antiepileptic. Do not stop abruptly (risk of rebound seizures). May cause drowsiness/dizziness—avoid driving/alcohol until you know the effect. Risk of metabolic acidosis, kidney stones, decreased sweating/heat intolerance (especially in hot weather/children), serious skin reactions, and mood changes/suicidal thoughts—seek medical help if symptoms occur. Use caution in kidney or liver disease; ensure adequate hydration. Contains sulfonamide—use caution in sulfa allergy.

Other CNS depressants (benzodiazepines, opioids, alcohol) may increase sedation; carbonic anhydrase inhibitors (topiramate, acetazolamide) increase risk of metabolic acidosis/kidney stones; CYP3A4 inducers (carbamazepine, phenytoin, phenobarbital, rifampicin) may reduce zonisamide levels; CYP3A4 inhibitors may increase levels.

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Zonisamide 100 mg (generic), Zonisun 100 Tablet, Zonisafe 100 Tablet, Zoniwax 100 Tablet, Zonamid 100 Tablet