Zyrova B 40 Tab 10S

Tablet

Management of high cholesterol (hypercholesterolemia/mixed dyslipidemia), reduction of LDL-C when diet and exercise alone are insufficient, to lower cardiovascular risk in eligible patients as advised by a doctor

Rosuvastatin is a statin (HMG‑CoA reductase inhibitor) that reduces cholesterol production in the liver and increases LDL clearance from blood. Ezetimibe reduces absorption of dietary and biliary cholesterol from the intestine. Together they produce a greater LDL‑cholesterol reduction than either alone.

Tablet for oral use. Take once daily at the same time each day, with or without food, as prescribed. Continue diet and lifestyle measures; do not stop without medical advice.

Headache, muscle pain (myalgia), weakness, abdominal pain, constipation, nausea, diarrhea, increased liver enzymes, dizziness

Prescription medicine. Report unexplained muscle pain/tenderness/weakness, dark urine or severe fatigue (risk of myopathy/rhabdomyolysis). Periodic liver function tests may be needed; avoid in active liver disease. Use caution in kidney disease, hypothyroidism, heavy alcohol use, and in elderly patients (higher muscle risk). Not recommended in pregnancy; discontinue if pregnancy occurs. Avoid breastfeeding. If persistent abdominal pain occurs, seek medical advice (rare pancreatitis).

Cyclosporine (contraindicated/avoid), gemfibrozil and other fibrates (increased myopathy risk), niacin (increased muscle risk), macrolide antibiotics and azole antifungals (may increase statin levels), protease inhibitors (increase rosuvastatin exposure), warfarin/other anticoagulants (monitor INR), antacids containing aluminum/magnesium (reduce rosuvastatin absorption; separate dosing)

Store below 25°C, protected from moisture and light. Keep in original strip and out of reach of children.

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