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Prescription requiredSilomCough & Cold preparation

Cofdoff Syrup

Phenylephrine (5mg) + Chlorpheniramine Maleate (2mcg) + Dextromethorphan Hydrobromide (10mg)

₹94MRP ₹98In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Cofdoff Syrup is used for symptomatic relief of cough and cold (dry or productive), throat irritation, chest congestion (depending on formulation).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Phenylephrine (5mg) + Chlorpheniramine Maleate (2mcg) + Dextromethorphan Hydrobromide (10mg)
Available variants: syrup 5mg + 2mcg + 10mg 100ML
Best price: ₹94 (₹0.94 per ml)
MRP: ₹98
Prescription: Required
Manufacturer: SILOM

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Cofdoff Syrup

Cofdoff Syrup contains Phenylephrine (5mg) + Chlorpheniramine Maleate (2mcg) + Dextromethorphan Hydrobromide (10mg). It belongs to the Antitussive/Expectorant/Antihistamine combination (varies by formulation) class of medicines.

Uses of Cofdoff Syrup

  • Symptomatic relief of cough and cold (dry or productive)
  • throat irritation
  • chest congestion (depending on formulation).

Key benefits

  • Relieves cough
  • Soothes throat irritation
  • Reduces cold/allergy symptoms
  • Helps loosen mucus and chest congestion (if expectorant present)

How Cofdoff Syrup works

Cough syrups usually combine one or more agents such as an antitussive to suppress cough, an expectorant/mucolytic to loosen mucus, and an antihistamine/decongestant to reduce allergy symptoms and nasal congestion. The exact mechanism depends on the active ingredients in the specific COFDOFF Syrup formulation.

How to take Cofdoff Syrup

Shake well before use. Measure dose with a calibrated cup/spoon and take as advised by a doctor. Can be taken with or without food; take after food if stomach upset occurs. Do not exceed recommended dose and avoid using multiple cough/cold products together unless advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. It can cause severe drowsiness, a fast heartbeat, confusion and, in children, agitation and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Cofdoff Syrup

Most side effects of Cofdoff are mild and settle as the body adjusts. Reported side effects include:

  • Drowsiness
  • dizziness
  • nausea
  • vomiting
  • stomach upset
  • dry mouth
  • constipation
  • headache
  • palpitations

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Cofdoff Syrup

PregnancyConsult doctor
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholAvoid
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverUse with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function.
Habit formingNo

Warnings and precautions

Exact warnings depend on ingredients. Many cough syrups can cause drowsiness—avoid driving/operating machinery if affected. Use with caution in children, elderly, pregnancy/breastfeeding, asthma/COPD, liver or kidney disease, thyroid disease, hypertension, glaucoma, enlarged prostate, and in patients taking sedatives. Do not use for prolonged cough (>7 days), recurrent fever, or cough with blood/shortness of breath; seek medical advice. Do not exceed dose; keep out of reach of children.

Do not take Cofdoff if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Codeine-containing preparations are not for children, or for anyone with breathing difficulty. The sedating antihistamines are not suitable for very young children, or for people with glaucoma or an enlarged prostate, without medical advice.

Interactions with other medicines

Alcohol and other CNS depressants (increased sedation), MAO inhibitors/antidepressants (some antihistamines/decongestants), antihypertensives (decongestants may raise BP), other cough/cold products containing similar ingredients (risk of overdose).

How to store Cofdoff Syrup

Store at room temperature (below 25°C), protected from light and moisture. Keep bottle tightly closed. Do not freeze.

Expert advice for Cofdoff Syrup

Drink plenty of water — it thins mucus better than any syrup. Steam inhalation helps congestion and costs nothing. Measure the dose with the cup supplied. Taking it at bedtime reduces the impact of any drowsiness. Identify and avoid your triggers where you can — dust, pollen, cold air.

Manufacturer and class

Manufacturer:
SILOM
Therapeutic class:
Cough & Cold preparation
Drug class:
Antitussive/Expectorant/Antihistamine combination (varies by formulation)

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Cofdoff Syrup FAQs

What is Cofdoff Syrup used for?
Cofdoff Syrup is commonly used for Symptomatic relief of cough and cold (dry or productive), throat irritation, chest congestion (depending on formulation). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Cofdoff Syrup?
Cofdoff Syrup contains Phenylephrine (5mg) + Chlorpheniramine Maleate (2mcg) + Dextromethorphan Hydrobromide (10mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Cofdoff Syrup?
Shake well before use. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Cofdoff Syrup work?
Cough syrups usually combine one or more agents such as an antitussive to suppress cough, an expectorant/mucolytic to loosen mucus, and an antihistamine/decongestant to reduce allergy symptoms and nasal congestion.
Is Cofdoff Syrup a prescription medicine?
Yes. Cofdoff Syrup is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Cofdoff Syrup?
The side effects reported most often with Cofdoff are Drowsiness, dizziness, nausea, vomiting, stomach upset. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Cofdoff Syrup be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Cofdoff.
Can I drink alcohol while taking Cofdoff Syrup?
Avoid
What if I miss a dose of Cofdoff Syrup?
Take it as soon as you remember.
Is Cofdoff Syrup habit forming?
No. Cofdoff Syrup is not known to be habit forming when taken as prescribed.
How much does Cofdoff Syrup cost on PingMeDoc Pharmacy?
Cofdoff Syrup starts at ₹94 (MRP ₹98) on PingMeDoc Pharmacy. Available in syrup 5mg + 2mcg + 10mg 100ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Cofdoff Syrup?
Cofdoff Syrup is manufactured by SILOM. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Cofdoff Syrup delivered?
Cofdoff Syrup is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Cofdoff Syrup, Quick facts

Salt
Phenylephrine (5mg) + Chlorpheniramine Maleate (2mcg) + Dextromethorphan Hydrobromide (10mg)
Form
syrup
Best price
₹94 (₹0.94 per ml)
MRP
₹98
Prescription
Required (Rx)
Schedule
Schedule H
Brand
SILOM
Manufacturer
SILOM
Therapeutic class
Cough & Cold preparation
Drug class
Antitussive/Expectorant/Antihistamine combination (varies by formulation)
Habit forming
No
Variants
syrup 5mg + 2mcg + 10mg 100ML
Delivery
Standard across India

References

The information on Cofdoff Syrup is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack insert, established medical literature on cough & cold combinations
  2. Indian pharmacy labeling practices
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Cofdoff Syrup.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.