
Ambroprl Respules
Pristine Pearl Pharma - Respule - 5 X2 ml
Prescription required
Ipratropium (500mcg) + Levosalbutamol (1.25mg)
Combimist L Respules is used for combimist-L Respules 2.5ml is used in the treatment of chronic obstructive pulmonary disease.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Combimist L Respules contains Ipratropium (500mcg) + Levosalbutamol (1.25mg). It belongs to the Inhaled bronchodilator / corticosteroid class of medicines.
Combimist-L Respules 2.5ml is used in the treatment of chronic obstructive pulmonary disease.
Combimist-L Respules 2.5ml is a combination of two medicines: Salbutamol/Albuterol and Ipratropium. Salbutamol/Albuterol is a bronchodilator while Ipratropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Combimist L are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Combimist-L Respules 2.5ml may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Combimist-L Respules 2.5ml is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | Combimist-L Respules 2.5ml may cause excessive drowsiness and calmness with alcohol. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | No interaction found/established |
| Liver | No interaction found/established |
| Habit forming | No |
Know which of your inhalers is the reliever and which is the preventer. A preventer must be used every day even when you feel well; a reliever is for symptoms. Seek emergency care if your reliever is not working, if you cannot speak a full sentence, or if you are using the reliever far more often than usual. Rinse your mouth with water and spit it out after every steroid inhaler dose to prevent thrush and hoarseness. Ask your doctor or pharmacist to watch your technique — poor technique is the commonest reason an inhaler seems not to work. Use a spacer if one has been advised, particularly for children.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler.
Beta blockers, including eye drops for glaucoma, can tighten the airways and reduce the effect of your reliever.
Store below 30°C, away from direct sunlight and heat. Do not puncture or burn the canister, even when empty. Keep out of the reach of children.
Keep a spare reliever and check the counter so you are not caught with an empty one. Follow your written asthma action plan if you have one. Do not stop a preventer because you feel better — that is the medicine working.
Medicines with the same active ingredient (Ipratropium (500mcg) + Levosalbutamol (1.25mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Combimist L Respules |
|---|---|---|---|
| Iprasure PulmulesALKEM LAB | 2.5ML | ₹17 | 34% cheaper |
| New Duoprl Ld RespulesPRISTINE PEARL PHARMA | respule · 5X2.5ML | ₹84 | 221% more |
| Dutaresp MistpulesJB CHEMICALS | 5X2.5ML | ₹128 | 389% more |

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The information on Combimist L Respules is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.