
Advog 0.2
Eris Life Sciences Pvt Ltd - 10 S
Prescription required
Gliclazide modified release 80 mg
Cyblex M 80 mg Tablet is used for type 2 diabetes mellitus (as an adjunct to diet and exercise) to improve glycaemic control.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Cyblex M 80 mg Tablet contains Gliclazide modified release 80 mg. It belongs to the Sulfonylurea (second generation) class of medicines.
Type 2 diabetes mellitus (as an adjunct to diet and exercise) to improve glycaemic control
Gliclazide is a sulfonylurea that stimulates insulin release from pancreatic beta cells by closing ATP-sensitive potassium channels. This increases insulin secretion and helps lower blood glucose levels, particularly post‑meal glucose.
Oral tablet. Take exactly as prescribed, usually once daily with breakfast/first main meal; swallow whole with water (do not crush/chew if modified-release). Maintain regular meals and monitor blood glucose; if a dose is missed, take the next dose at the usual time—do not double.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Cyblex M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended / Consult doctor (insulin is generally preferred in pregnancy) |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid (may increase risk of hypoglycaemia) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Risk of hypoglycaemia especially with missed meals, strenuous exercise, alcohol intake, dose errors, renal/hepatic impairment, or when combined with other antidiabetic drugs. Use with caution in elderly, malnourished patients, and those with kidney or liver disease. Not indicated for type 1 diabetes or diabetic ketoacidosis. Seek medical help for severe hypoglycaemia, allergic reactions, jaundice, or unusual bruising/bleeding. During acute illness/surgery, treatment may need adjustment.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease.
Other antidiabetics (insulin, metformin, DPP-4 inhibitors, GLP-1 agonists) increase hypoglycaemia risk; alcohol increases hypoglycaemia risk; beta-blockers may mask hypoglycaemia symptoms; corticosteroids and thiazide diuretics may raise glucose; fluconazole and some macrolide/quinolone antibiotics can increase hypoglycaemic effect; warfarin effect may be altered—monitor INR
Store below 25°C, in a dry place protected from light and moisture. Keep in original blister pack and out of reach of children.
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes.

Eris Life Sciences Pvt Ltd - 10 S
Prescription required
Eris Life Sciences Pvt Ltd - 10 S
Prescription required
Eris Life Sciences Pvt Ltd - 10 S
Prescription required
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The information on Cyblex M 80 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.