
Actigut Caps
Alembic Pharma - Capsule - 10 S
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Rabeprazole (20mg) + Diclofenac (100mg)
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D Kool Capsule is used for d Kool Capsule is used for pain relief.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
D Kool Capsule contains Rabeprazole (20mg) + Diclofenac (100mg). It belongs to the Proton pump inhibitor and Non-steroidal anti-inflammatory drug class of medicines.
D Kool Capsule is used for pain relief.
D Kool Capsule is a combination of two medicines: Diclofenac and Rabeprazole which relieve pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain, fever and inflammation (redness and swelling). Rabeprazole is a proton-pump inhibitor which prevents damage to the stomach lining caused by Diclofenac.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. D Kool Capsule is to be taken empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of D Kool are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | D Kool Capsule is unsafe to use during pregnancy.<br>There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor. |
|---|---|
| Breastfeeding | D Kool Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | D Kool Capsule should be used with caution in patients with kidney disease. Dose adjustment of D Kool Capsule may be needed. Please consult your doctor. |
| Liver | D Kool Capsule should be used with caution in patients with liver disease. Dose adjustment of D Kool Capsule may be needed. Please consult your doctor.<br>Regular monitoring of liver function tests is recommended in patients with liver disease if this medicine is to be taken for a long time. |
| Habit forming | No |
Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.
Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take it before breakfast, not after a meal. Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking — these do as much as the tablet for reflux. Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache.

Alembic Pharma - Capsule - 10 S
Save ₹9
Prescription required

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Prescription required
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The information on D Kool Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.