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Paroxetine (37.5mg)
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Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Depaxil CR 37.5 Tablet is used for depaxil CR 37.5 Tablet is used in the treatment of depression, obsessive-compulsive disorder, phobia and post traumatic stress disorder.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Depaxil CR 37.5 Tablet.
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Depaxil CR 37.5 Tablet
tablet - 37.5mg - 10 S
₹373
₹37.32 per tablet
IPCA LABORATORIES LTD` · tablet - 37.5mg - 15 S · Rx
₹533
₹35.57 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Depaxil CR 37.5 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Depaxil CR 37.5 Tablet contains Paroxetine (37.5mg). It belongs to the Antidepressant class of medicines.
Depaxil CR 37.5 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms in depression and relieves symptoms of panic and obsessive disorders.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depaxil CR 37.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Depaxil CR are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Depaxil CR 37.5 Tablet is highly unsafe to use during pregnancy.<br>Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor. |
|---|---|
| Breastfeeding | Depaxil CR 37.5 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Depaxil CR 37.5 Tablet may cause excessive drowsiness and calmness with alcohol. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Depaxil CR 37.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Depaxil CR 37.5 Tablet may be needed. Please consult your doctor. |
| Liver | Depaxil CR 37.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Depaxil CR 37.5 Tablet may be needed. Please consult your doctor. |
| Habit forming | No |
These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Often a preferred treatment of anxious depression as well as major depressive disorder with anxiety disoders.</li> <li><div>It can take 2-3 weeks for Pexep CR 37.5 Tablet to start working.</div></li> <li><div>Do not stop treatment suddenly as this may cause a stomach upset, flu-like withdrawal symptoms and sleep disturbance.</div></li> <li><div>If your doctor asks you to stop Pexep CR 37.5 Tablet, you should reduce the dose slowly over 4 weeks.</div></li> <li><div>Avoid consuming alcohol when taking the Pexep CR 37.5 Tablet, as it may cause excessive drowsiness and calmness.</div></li> <li><div>The addiction/dependence potential of Pexep CR 37.5 Tablet is very less.</div></li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Paroxetine (37.5mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Depaxil CR 37.5 Tablet |
|---|---|---|---|
| Xet CR 37.5 TabletZYDUS HEALTHCARE PHARMA | tablet · 10`S | ₹406 | 9% more |
| Paxinta CR 37.5 TabletIntas Pharmaceuticals Ltd | tablet · 10`S | ₹419 | 12% more |
| Pari CR 37.5 TabletIPCA LABORATORIES LTD` | tablet · 15`S | ₹533 | 43% more |

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The information on Depaxil CR 37.5 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.