Skip to main content
PingMeDoc
Prescription requiredAlkem LabAntidepressant

Depaxil CR 37.5 Tablet

Paroxetine (37.5mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Xet CR 37.5 Tablet₹406View
  • Paxinta CR 37.5 Tablet₹419View
  • Pari CR 37.5 Tablet₹533View

Depaxil CR 37.5 Tablet is used for depaxil CR 37.5 Tablet is used in the treatment of depression, obsessive-compulsive disorder, phobia and post traumatic stress disorder.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Paroxetine (37.5mg)
Available variants: tablet 37.5mg 10`S
Best price: ₹373 (₹37.32 per tablet)
MRP: ₹393
Prescription: Required
Manufacturer: ALKEM LAB

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Depaxil CR 37.5 Tablet.

You are viewing

Depaxil CR 37.5 Tablet

tablet - 37.5mg - 10 S

₹373

₹37.32 per tablet

  • Pari CR 37.5 Tab

    IPCA LABORATORIES LTD` · tablet - 37.5mg - 15 S · Rx

    ₹533

    ₹35.57 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Depaxil CR 37.5 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Depaxil CR 37.5 Tablet

Depaxil CR 37.5 Tablet contains Paroxetine (37.5mg). It belongs to the Antidepressant class of medicines.

Uses of Depaxil CR 37.5 Tablet

  • Depaxil CR 37.5 Tablet is used in the treatment of depression
  • obsessive-compulsive disorder
  • phobia and post traumatic stress disorder.

Key benefits

  • Effective for depression and anxiety disorders
  • Also relieves nerve pain and prevents migraine
  • Usually taken once a day

How Depaxil CR 37.5 Tablet works

Depaxil CR 37.5 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms in depression and relieves symptoms of panic and obsessive disorders.

How to take Depaxil CR 37.5 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depaxil CR 37.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Depaxil CR 37.5 Tablet

Most side effects of Depaxil CR are mild and settle as the body adjusts. Reported side effects include:

  • Low sexual desire Delayed ejaculation Insomnia (difficulty in sleeping) Vomiting Orthostatic hypotension (sudden lowering of blood pressure on standing) Nausea Dryness in mouth Weight gain Erectile dysfunction Stomach upset

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Depaxil CR 37.5 Tablet

PregnancyDepaxil CR 37.5 Tablet is highly unsafe to use during pregnancy.<br>Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
BreastfeedingDepaxil CR 37.5 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
AlcoholDepaxil CR 37.5 Tablet may cause excessive drowsiness and calmness with alcohol.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyDepaxil CR 37.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Depaxil CR 37.5 Tablet may be needed. Please consult your doctor.
LiverDepaxil CR 37.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Depaxil CR 37.5 Tablet may be needed. Please consult your doctor.
Habit formingNo

Warnings and precautions

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Do not take Depaxil CR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

How to store Depaxil CR 37.5 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Depaxil CR 37.5 Tablet

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Often a preferred treatment of anxious depression as well as major depressive disorder with anxiety disoders.</li> <li><div>It can take 2-3 weeks for Pexep CR 37.5 Tablet to start working.</div></li> <li><div>Do not stop treatment suddenly as this may cause a stomach upset, flu-like withdrawal symptoms and sleep disturbance.</div></li> <li><div>If your doctor asks you to stop Pexep CR 37.5 Tablet, you should reduce the dose slowly over 4 weeks.</div></li> <li><div>Avoid consuming alcohol when taking the Pexep CR 37.5 Tablet, as it may cause excessive drowsiness and calmness.</div></li> <li><div>The addiction/dependence potential of Pexep CR 37.5 Tablet is very less.</div></li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
ALKEM LAB
Therapeutic class:
Antidepressant
Drug class:
Antidepressant

Substitutes for Depaxil CR 37.5 Tablet

Medicines with the same active ingredient (Paroxetine (37.5mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Depaxil CR 37.5 Tablet
Xet CR 37.5 TabletZYDUS HEALTHCARE PHARMAtablet · 10`S₹4069% more
Paxinta CR 37.5 TabletIntas Pharmaceuticals Ltdtablet · 10`S₹41912% more
Pari CR 37.5 TabletIPCA LABORATORIES LTD`tablet · 15`S₹53343% more
See all substitutes and alternatives

More from Alkem Lab

View categories
A To Z Amino Tab
5% off

A To Z Amino Tab

Alkem Lab - Tablet - 15 S

₹257₹270

Save ₹13

A To Z Gold Cap
5% off

A To Z Gold Cap

Alkem Lab - Capsule - 15 S

₹229₹241

Save ₹12

A To Z Ns New Drops
5% off

A To Z Ns New Drops

Alkem Lab - Drop - 30 ml

₹138₹145

Save ₹7

A To Z Woman Caps
5% off

A To Z Woman Caps

Alkem Lab - Capsule - 15 S

₹371₹390

Save ₹19

Alkepin Odt 100
5% off

Alkepin Odt 100

Alkem Lab - 10 S

₹86₹91

Save ₹5

Alkepin Odt 12.5

Alkepin Odt 12.5

Alkem Lab - 10 S

₹31₹32

Save ₹1

7% off

Alkepin Odt 25

Alkem Lab - 10 S

₹28₹30

Save ₹2

5% off

Alkepin Odt 50

Alkem Lab - 10 S

₹53₹56

Save ₹3

More in Antidepressants

View categories
Aceco Ps Tab
5% offRx

Aceco Ps Tab

Lewin Healthcare - Tablet - 100mg + 325mg - 10 S

₹109₹115

Save ₹6

Prescription required

6% offRx

Alzolam 0.5

Sun Pharma - 10 S

₹46₹49

Save ₹3

Prescription required

Available in store

In-store
Anaflam-Th4 Tab
5% offRx

Anaflam-Th4 Tab

Albert David Ltd - Tablet - 100mg + 325mg + 4mg - 10 S

₹208₹219

Save ₹11

Prescription required

5% offRx

Atrest 25MG Tab

Centaur Pharmaceuticals Ltd - Tablet - 25 mg - 10 S

₹373₹393

Save ₹20

Prescription required

Briv Syrup
5% offRx

Briv Syrup

Dr Reddys Laboratories Ltd - Syrup - 10mg - 100 ml

₹424₹446

Save ₹22

Prescription required

Cismatrix Tab
5% offRx

Cismatrix Tab

Kalpa Health Care Pvt Ltd - Tablet - 10 S

₹190₹200

Save ₹10

Prescription required

5% offRx

Clonil 75 SR

Intas Pharmaceuticals Ltd - 15 S

₹252₹266

Save ₹14

Prescription required

Divalex Od - 250MG Tab
5% offRx

Divalex Od - 250MG Tab

Crescent Forumulations Pvt Ltd - Tablet - 250 mg - 10 S

₹100₹105

Save ₹5

Prescription required

Popular on PingMeDoc Pharmacy

View categories
Wysolone Dt 5 Tablet
9% offRx

Wysolone Dt 5 Tablet

Pfizer Ltd - Tablet - 15 Tablet

₹10₹11

Save ₹1

Prescription required

D9 Hairblendz Nutritional Hair Kit
5% off

D9 Hairblendz Nutritional Hair Kit

D9 Healthcare Llp - Kit

₹1,581₹1,664

Save ₹83

Vaseline Jelly 12GM

12 G

₹10
15% off

Artery Forceps 6"Cd.Pak

1*1

₹510₹600

Save ₹90

Rbx Aid Plaster

100 S

₹4
7% off

Funplay Condom Choco 3S

Funplay - 1*3*30

₹28₹30

Save ₹2

15% off

Adson Forceps

1

₹298₹350

Save ₹52

Rbx Aid Plaster New

1

₹4₹4

Depaxil CR 37.5 Tablet FAQs

What is Depaxil CR 37.5 Tablet used for?
Depaxil CR 37.5 Tablet is commonly used for Depaxil CR 37.5 Tablet is used in the treatment of depression, obsessive-compulsive disorder, phobia and post traumatic stress disorder. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Depaxil CR 37.5 Tablet?
Depaxil CR 37.5 Tablet contains Paroxetine (37.5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Depaxil CR 37.5 Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Depaxil CR 37.5 Tablet work?
Depaxil CR 37.5 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant.
Is Depaxil CR 37.5 Tablet a prescription medicine?
Yes. Depaxil CR 37.5 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Depaxil CR 37.5 Tablet?
The side effects reported most often with Depaxil CR are Low sexual desire Delayed ejaculation Insomnia (difficulty in sleeping) Vomiting Orthostatic hypotension (sudden lowering of blood pressure on standing) Nausea Dryness in mouth Weight gain Erectile dysfunction Stomach upset. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Depaxil CR 37.5 Tablet be taken during pregnancy?
Depaxil CR 37.5 Tablet is highly unsafe to use during pregnancy.<br>Human and animal studies have shown significant adverse effects on the foetus. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Depaxil CR.
Can I drink alcohol while taking Depaxil CR 37.5 Tablet?
Depaxil CR 37.5 Tablet may cause excessive drowsiness and calmness with alcohol.
What if I miss a dose of Depaxil CR 37.5 Tablet?
Take it as soon as you remember.
Is Depaxil CR 37.5 Tablet habit forming?
No. Depaxil CR 37.5 Tablet is not known to be habit forming when taken as prescribed.
How much does Depaxil CR 37.5 Tablet cost on PingMeDoc Pharmacy?
Depaxil CR 37.5 Tablet starts at ₹373 (MRP ₹393) on PingMeDoc Pharmacy. Available in tablet 37.5mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Depaxil CR 37.5 Tablet?
Depaxil CR 37.5 Tablet is manufactured by ALKEM LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Depaxil CR 37.5 Tablet delivered?
Depaxil CR 37.5 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Depaxil CR 37.5 Tablet, Quick facts

Salt
Paroxetine (37.5mg)
Form
tablet
Best price
₹373 (₹37.32 per tablet)
MRP
₹393
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ALKEM LAB
Manufacturer
ALKEM LAB
Therapeutic class
Antidepressant
Drug class
Antidepressant
Habit forming
No
Variants
tablet 37.5mg 10`S
Delivery
Standard across India

References

The information on Depaxil CR 37.5 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Depaxil CR 37.5 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.