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Prescription requiredLupin LabAnti-asthmatic

Esiflo 250 Trans

Fluticasone (50mcg) + Salmeterol (25mcg)

₹543MRP ₹596In stock
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Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Esiflo 250 Trans is used for esiflo 50 Transhaler is used in the treatment of asthma and chronic obstructive pulmonary disease.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Fluticasone (50mcg) + Salmeterol (25mcg)
Available variants: NA 30`S
Best price: ₹543
MRP: ₹596
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Esiflo 250 Trans

Esiflo 250 Trans contains Fluticasone (50mcg) + Salmeterol (25mcg). It belongs to the Inhaled bronchodilator / corticosteroid class of medicines.

Uses of Esiflo 250 Trans

Esiflo 50 Transhaler is used in the treatment of asthma and chronic obstructive pulmonary disease.

Key benefits

  • Acts directly in the lungs with minimal effect elsewhere
  • Prevents attacks when used daily as a preventer
  • Portable and fast acting

How Esiflo 250 Trans works

Esiflo 50 Transhaler is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

How to take Esiflo 250 Trans

Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Esiflo 250 Trans

Most side effects of Esiflo are mild and settle as the body adjusts. Reported side effects include:

  • Throat irritation
  • Hoarse voice
  • Oral thrush
  • Tremor
  • Fast heartbeat
  • Headache

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Esiflo 250 Trans

PregnancyEsiflo 50 Transhaler may be unsafe to use during pregnancy.<br/>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingEsiflo 50 Transhaler is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholAlcohol may worsen the side effects of this medicine. Limit it.
DrivingNot expected to affect your ability to drive.
KidneyNo dose change is usually needed in kidney disease.
LiverUse with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function.
Habit formingNo

Warnings and precautions

Know which of your inhalers is the reliever and which is the preventer. A preventer must be used every day even when you feel well; a reliever is for symptoms. Seek emergency care if your reliever is not working, if you cannot speak a full sentence, or if you are using the reliever far more often than usual. Rinse your mouth with water and spit it out after every steroid inhaler dose to prevent thrush and hoarseness. Ask your doctor or pharmacist to watch your technique — poor technique is the commonest reason an inhaler seems not to work. Use a spacer if one has been advised, particularly for children.

Do not take Esiflo if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler.

Interactions with other medicines

Beta blockers, including eye drops for glaucoma, can tighten the airways and reduce the effect of your reliever.

How to store Esiflo 250 Trans

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Esiflo 250 Trans

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Esiflo 50 Transhaler is a combination of two medicines that opens the airways and makes it easier to breathe.</li> <li>This medicine is for inhalation only. The tablet should not be swallowed.</li> <li>It should be taken at the same time each day.</li> <li>It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. </li> <li>Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.</li> <li>Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.</li> <li>Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.</li> <li>Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Esiflo 50 Transhaler can lower blood potassium level.</li> <li>Only miniscule amounts of Esiflo 50 Transhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
Anti-asthmatic
Drug class:
Inhaled bronchodilator / corticosteroid

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Esiflo 250 Trans FAQs

What is Esiflo 250 Trans used for?
Esiflo 250 Trans is commonly used for Esiflo 50 Transhaler is used in the treatment of asthma and chronic obstructive pulmonary disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Esiflo 250 Trans?
Esiflo 250 Trans contains Fluticasone (50mcg) + Salmeterol (25mcg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Esiflo 250 Trans?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Esiflo 250 Trans work?
Esiflo 50 Transhaler is a combination of two medicines: Salmeterol and Fluticasone Propionate.
Is Esiflo 250 Trans a prescription medicine?
Yes. Esiflo 250 Trans is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Esiflo 250 Trans?
The side effects reported most often with Esiflo are Throat irritation, Hoarse voice, Oral thrush, Tremor, Fast heartbeat. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Esiflo 250 Trans be taken during pregnancy?
Esiflo 50 Transhaler may be unsafe to use during pregnancy.<br/>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Esiflo.
Can I drink alcohol while taking Esiflo 250 Trans?
Alcohol may worsen the side effects of this medicine.
What if I miss a dose of Esiflo 250 Trans?
Take it as soon as you remember.
Is Esiflo 250 Trans habit forming?
No. Esiflo 250 Trans is not known to be habit forming when taken as prescribed.
How much does Esiflo 250 Trans cost on PingMeDoc Pharmacy?
Esiflo 250 Trans starts at ₹543 (MRP ₹596) on PingMeDoc Pharmacy. Available in NA 30`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Esiflo 250 Trans?
Esiflo 250 Trans is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Esiflo 250 Trans delivered?
Esiflo 250 Trans is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Esiflo 250 Trans, Quick facts

Salt
Fluticasone (50mcg) + Salmeterol (25mcg)
Best price
₹543
MRP
₹596
Prescription
Required (Rx)
Schedule
Schedule H
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
Anti-asthmatic
Drug class
Inhaled bronchodilator / corticosteroid
Habit forming
No
Variants
NA 30`S
Delivery
Standard across India

References

The information on Esiflo 250 Trans is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Esiflo 250 Trans.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.