
Ab Flo Caps
Lupin Lab - Capsule - 100mg - 15 S
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Glimepiride 3 mg + Metformin Hydrochloride 1000 mg (Sustained Release)
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Glador M 3 Forte is used for type 2 diabetes mellitus when diet and exercise alone are not enough; helps control high blood sugar and improves glycaemic control (often in patients needing combination therapy).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Glador M 3 Forte contains Glimepiride 3 mg + Metformin Hydrochloride 1000 mg (Sustained Release). It belongs to the Sulfonylurea + Biguanide (SR combination) class of medicines.
Type 2 diabetes mellitus when diet and exercise alone are not enough; helps control high blood sugar and improves glycaemic control (often in patients needing combination therapy).
Glimepiride (a sulfonylurea) stimulates the pancreas to release insulin. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, lowering blood sugar levels.
Oral tablet. Take exactly as prescribed, usually once daily with/after meals (preferably with the main meal) to reduce stomach upset. Swallow whole; do not crush/chew if SR. Monitor blood glucose regularly.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Glador M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended / Consult doctor (insulin preferred in pregnancy; use only if clearly needed) |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Risk of hypoglycaemia (higher with missed meals, alcohol, excessive exercise); lactic acidosis is a rare but serious risk with metformin—seek urgent care for fast breathing, severe weakness, drowsiness, abdominal pain. Avoid/use with caution in kidney impairment; dose adjustment and periodic renal function monitoring required. Use caution in liver disease, heart failure, dehydration, severe infection, or before major surgery. Temporarily stop metformin around iodinated contrast procedures as advised by doctor. Do not use in type 1 diabetes or diabetic ketoacidosis.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Alcohol (increases hypoglycaemia/lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia symptoms), corticosteroids/thiazide diuretics (raise glucose), ACE inhibitors (may increase hypoglycaemia), cimetidine (raises metformin levels), iodinated contrast media (kidney injury/lactic acidosis risk), NSAIDs and salicylates (may enhance hypoglycaemia)
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Lupin Lab - Capsule - 100mg - 15 S
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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.