
Acewave P Tab
Cresha Lifesciences - Tablet - 100mg + 325mg - 10 S
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Glimepiride 0.5 mg + Metformin hydrochloride (strength unknown)
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Glimiscore-M 0.5 Tablet is used for type 2 diabetes mellitus (adult) when diet and exercise alone are insufficient; used to improve glycaemic control.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Glimiscore-M 0.5 Tablet contains Glimepiride 0.5 mg + Metformin hydrochloride (strength unknown). It belongs to the Sulfonylurea + Biguanide class of medicines.
Type 2 diabetes mellitus (adult) when diet and exercise alone are insufficient; used to improve glycaemic control.
Glimepiride (a sulfonylurea) stimulates the pancreas to release insulin and improves peripheral insulin sensitivity. Metformin reduces glucose production in the liver and decreases intestinal glucose absorption while improving insulin sensitivity.
Take orally as advised by a doctor, preferably with meals to reduce stomach upset and risk of low sugar. Swallow tablet whole with water; do not crush/chew unless advised. Monitor blood glucose regularly and follow diet/exercise plan.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Glimiscore-M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended; consult doctor (insulin is usually preferred in pregnancy). |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Risk of hypoglycaemia (more likely with missed meals, excess exercise, alcohol, elderly, or kidney/liver impairment). Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, muscle pain, unusual sleepiness, or abdominal discomfort. Use with caution/avoid in severe renal impairment, severe liver disease, dehydration, severe infection, hypoxia, or alcoholism. Temporarily stop metformin before and after iodinated contrast studies or major surgery as advised. Regularly monitor kidney function, liver function, and vitamin B12 with long-term use.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Alcohol (increases hypoglycaemia/lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia symptoms), corticosteroids/thiazide diuretics (raise glucose), ACE inhibitors (may enhance hypoglycaemia), fluoroquinolones (glucose disturbances), rifampicin (reduces effect), azole antifungals and macrolides (may increase sulfonylurea effect), iodinated contrast media (lactic acidosis risk with metformin), cimetidine (increases metformin levels)
Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

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The information on Glimiscore-M 0.5 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.