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Cresha Lifesciences - Tablet - 100mg + 325mg - 10 S
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Glimepiride 1 mg + Metformin Hydrochloride (SR) 500 mg + Voglibose 0.2 mg
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Glimiscore Mv1 Tablet is used for type 2 diabetes mellitus when diet and exercise alone or dual therapy is insufficient; helps control post-meal and fasting blood glucose.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Glimiscore Mv1 Tablet contains Glimepiride 1 mg + Metformin Hydrochloride (SR) 500 mg + Voglibose 0.2 mg. It belongs to the Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor class of medicines.
Type 2 diabetes mellitus when diet and exercise alone or dual therapy is insufficient; helps control post-meal and fasting blood glucose.
Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin SR improves insulin sensitivity and reduces glucose production by the liver. Voglibose inhibits intestinal alpha-glucosidase enzymes, delaying carbohydrate absorption and reducing post-meal glucose spikes.
Oral tablet. Take exactly as prescribed, typically once daily with/after a main meal (often breakfast) to reduce stomach upset and risk of low sugar. Swallow whole (do not crush/chew) due to sustained-release metformin; follow diet and exercise advice and monitor blood glucose.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Glimiscore Mv1 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended; consult doctor (insulin preferred in pregnancy). |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid (increases risk of hypoglycaemia and metformin-associated lactic acidosis). |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
May cause hypoglycaemia (especially if meals are skipped, with alcohol, or with other antidiabetics); carry a quick source of sugar. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, severe infection, dehydration, heavy alcohol use, or heart/liver failure; kidney function monitoring advised. Temporarily stop metformin around iodinated contrast procedures or major surgery as advised by doctor. Use caution in elderly and in people with renal/hepatic impairment. Voglibose may cause significant GI gas/diarrhoea; avoid in intestinal obstruction or severe digestive disorders. Seek medical help for severe weakness, breathing difficulty, persistent vomiting, or signs of pancreatitis (severe abdominal pain).
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.
Alcohol, insulin/other antidiabetics (increased hypoglycaemia), beta-blockers (mask hypoglycaemia), corticosteroids and thiazide diuretics (raise glucose), ACE inhibitors (may increase hypoglycaemia), rifampicin (reduces sulfonylurea effect), azole antifungals/clarithromycin (increase sulfonylurea levels), iodinated contrast media (metformin-related lactic acidosis risk), cimetidine (increases metformin levels)
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. Take it with the first mouthful of your meal so it can act on that meal. Expect some wind in the first weeks; it usually settles.

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The information on Glimiscore Mv1 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.