Humiglim M2 Dapa Tablet

Composition of Humiglim M2 Dapa Tablet

Humiglim M2 Dapa Tablet contains Glimepiride 2 mg + Metformin (as hydrochloride) 500 mg + Dapagliflozin 10 mg (tablet). It belongs to the Sulfonylurea + Biguanide + SGLT2 inhibitor class of medicines.

Uses of Humiglim M2 Dapa Tablet

Type 2 diabetes mellitus—adjunct to diet and exercise to improve glycaemic control in adults when dual/monotherapy is inadequate.

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin sensitivity and reduces liver glucose output
• Promotes glucose excretion via urine
• Helps achieve better HbA1c control
• May support modest weight reduction with SGLT2 component

How Humiglim M2 Dapa Tablet works

Glimepiride (sulfonylurea) increases insulin release from pancreatic beta cells. Metformin reduces hepatic glucose production and improves insulin sensitivity. Dapagliflozin (SGLT2 inhibitor) increases urinary glucose excretion by reducing glucose reabsorption in the kidneys.

How to take Humiglim M2 Dapa Tablet

Oral tablet; take exactly as prescribed. Usually taken once daily with food (preferably with breakfast) to reduce stomach upset and hypoglycaemia risk; swallow whole with water. Regularly monitor blood glucose; do not stop or change dose without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It can cause dehydration and a fall in blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Humiglim M2 Dapa Tablet

Most side effects of Humiglim M2 Dapa are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• dizziness
• headache
• nausea
• diarrhoea
• abdominal pain
• loss of appetite
• genital fungal infection
• urinary tract infection
• increased urination
• thirst

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Humiglim M2 Dapa Tablet

Warnings and precautions

Prescription-only antidiabetic. Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise, elderly, renal/hepatic impairment). Metformin: rare lactic acidosis risk—avoid in severe kidney disease, severe liver disease, hypoxia, dehydration; temporarily stop before/after iodinated contrast and major surgery as advised. Dapagliflozin: risk of genital mycotic infections, UTIs, dehydration/low BP, ketoacidosis (can occur with near-normal glucose), acute kidney injury; maintain hydration and stop during acute illness/fasting/surgery per clinician advice. Monitor renal function, HbA1c, and signs of infection; use caution in heart failure/diuretics. Not for type 1 diabetes or diabetic ketoacidosis.

Do not take Humiglim M2 Dapa if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with severe kidney disease.

Interactions with other medicines

Insulin/other antidiabetics (increased hypoglycaemia risk), diuretics (dehydration/hypotension risk with dapagliflozin), ACE inhibitors/ARBs/NSAIDs (may affect kidney function), corticosteroids and thyroid hormones (raise glucose), rifampicin (may reduce glimepiride effect), azole antifungals/clarithromycin (may increase sulfonylurea effect), alcohol (hypoglycaemia and lactic acidosis risk), iodinated contrast media (lactic acidosis risk with metformin)

How to store Humiglim M2 Dapa Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Humiglim M2 Dapa Tablet

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine.

Manufacturer and class

Manufacturer:

VERSE LIFESCIENCES

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide + SGLT2 inhibitor