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Blue Cross Laboratories Pvt Ltd - 15 S
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Glimepiride (2mg) + Metformin (500mg)
K-Glim M2 is used for k Glim M2 Tablet is used in the treatment of type 2 diabetes.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
K-Glim M2 contains Glimepiride (2mg) + Metformin (500mg). It belongs to the Sulfonylurea and Biguanide class of medicines.
K Glim M2 Tablet is used in the treatment of type 2 diabetes.
K Glim M2 Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin.Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the bodys sensitivity to insulin.
Use it as advised by your doctor or check the label for directions before use. K Glim M2 Tablet is to be taken with food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of K-Glim M2 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | K Glim M2 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. |
|---|---|
| Breastfeeding | K Glim M2 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Alcohol | It is unsafe to consume alcohol with K Glim M2 Tablet . |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | K Glim M2 Tablet should be used with caution in patients with kidney disease. Dose adjustment of K Glim M2 Tablet may be needed. Please consult your doctor.Use of K Glim M2 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine. |
| Liver | K Glim M2 Tablet should be used with caution in patients with liver disease. Dose adjustment of K Glim M2 Tablet may be needed. Please consult your doctor.K Glim M2 Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease. |
| Habit forming | No |
If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.</div></li> <li>You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with K Glim M2 Tablet PR.</li> <li>Take it with food to lower your chance of having an upset stomach.</li> <li>Monitor your blood sugar level regularly while you are taking this medicine. </li> <li>Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.</li> <li>It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. </li> <li>Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as K Glim M2 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.</li> <li>Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).</li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.
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The information on K-Glim M2 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.