Linabite M 5/500 Tablet

Composition of Linabite M 5/500 Tablet

Linabite M 5/500 Tablet contains Linagliptin 5 mg + Metformin 500 mg (as Metformin Hydrochloride). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Linabite M 5/500 Tablet

• Treatment of type 2 diabetes mellitus to improve glycaemic control (along with diet and exercise)
• especially when metformin alone or linagliptin alone is insufficient

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin response in a glucose-dependent way
• Reduces hepatic glucose production
• Helps improve HbA1c with low hypoglycaemia risk when used without insulin/secretagogues

How Linabite M 5/500 Tablet works

Linagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), leading to increased insulin release and reduced glucagon in a glucose-dependent manner. Metformin decreases hepatic glucose production and improves peripheral insulin sensitivity, thereby lowering blood glucose.

How to take Linabite M 5/500 Tablet

Oral tablet; take exactly as prescribed. Usually taken with meals to reduce stomach upset; swallow whole with water. Do not crush/chew; follow dosing schedule advised by doctor and monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Linabite M 5/500 Tablet

Most side effects of Linabite M 5/500 are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• diarrhea
• abdominal pain
• loss of appetite
• metallic taste
• headache
• nasopharyngitis
• cough
• dizziness
• hypoglycaemia (more likely with other antidiabetics)
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Linabite M 5/500 Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Metformin can rarely cause lactic acidosis—risk increases with severe kidney disease, dehydration, sepsis, alcohol excess, liver disease, or hypoxia; assess renal function before and during therapy. Temporarily stop metformin around iodinated contrast procedures and major surgery as advised by doctor. Use caution in elderly and in patients with renal/hepatic impairment; seek care for severe abdominal pain (possible pancreatitis), persistent vomiting, rapid breathing, or unusual muscle pain/weakness.

Do not take Linabite M 5/500 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, cationic drugs affecting renal tubular secretion (e.g., cimetidine), diuretics and ACE inhibitors (may affect renal function), corticosteroids and sympathomimetics (raise glucose), insulin/sulfonylureas (increase hypoglycaemia risk), rifampicin (may reduce linagliptin effect via P-gp/CYP induction)

How to store Linabite M 5/500 Tablet

Store below 25°C, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Linabite M 5/500 Tablet

It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

CORONA REMEDIES PVT LTD

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide