
Acuclav 375
Macleods Pharmaceuticals Pvt Ltd - 10 S
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Azithromycin (250mg) + Cefpodoxime (200mg)
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Macpod Az is used for bacterial infections.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Macpod Az contains Azithromycin (250mg) + Cefpodoxime (200mg). It belongs to the Macrolide and Cephalosporin class of medicines.
Bacterial infections
Macpod Az Tablet is a combination of two antibiotics: Cefpodoxime Proxetil and Azithromycin. Cefpodoxime Proxetil works by preventing the formation of the bacterial protective covering which is essential for the survival of the bacteria. Azithromycin stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.
Take exactly as prescribed by your doctor.
Most side effects of Macpod Az are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Macpod AZ Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. |
|---|---|
| Breastfeeding | Macpod AZ Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.There may be a possibility of diarrhea or rash in the baby. |
| Alcohol | It is unsafe to consume alcohol with Macpod AZ Tablet. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Macpod AZ Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Macpod AZ Tablet may be needed. Please consult your doctor. |
| Liver | Macpod AZ Tablet should be used with caution in patients with liver disease. Dose adjustment of Macpod AZ Tablet may be needed. Please consult your doctor. |
| Habit forming | No |
Finish the whole course even after you feel better. Tell your doctor if you have a heart rhythm problem or take a medicine for one — this group can affect the heart's electrical timing. Report severe or watery loose motions during or after the course rather than treating them yourself. Finish the whole course even after you feel better — stopping early breeds resistant bacteria. Tell your doctor if you have ever had a severe reaction to penicillin; a small proportion of people react to both groups. Several medicines in this group are on Schedule H1 precisely because overuse drives antibiotic resistance. Take it only when a doctor has prescribed it for you.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to macrolide antibiotics, or with certain heart rhythm disorders. Not for anyone with a known allergy to cephalosporin antibiotics.
Interacts with a long list of medicines, including statins, some heart medicines and blood thinners — tell your doctor everything you take. Antacids reduce absorption; separate them by a couple of hours. Antacids, iron and zinc reduce absorption — separate them by a couple of hours. Tell your doctor if you take a blood thinner.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take it at the same time each day and complete the course. Taking it with food reduces nausea unless the pack says to take it on an empty stomach. Space the doses evenly and complete the course. Keep the reconstituted syrup as the pharmacist instructed and discard it after the stated number of days.

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The information on Macpod Az is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.