Mediformin-SR Tablet

Composition of Mediformin-SR Tablet

Mediformin-SR Tablet contains Metformin (500mg). It belongs to the Biguanide (insulin sensitizer) class of medicines.

Uses of Mediformin-SR Tablet

• Type 2 diabetes mellitus (to control blood glucose)
• Prediabetes/insulin resistance (as advised by doctor)
• Polycystic ovary syndrome (PCOS) related insulin resistance (off-label
• as prescribed)

Key benefits

• Helps control fasting and post-meal blood sugar
• Improves insulin sensitivity and reduces insulin resistance
• Low risk of hypoglycaemia when used alone
• May help with weight neutrality/weight control
• Reduces risk of diabetes-related complications with good control

How Mediformin-SR Tablet works

Metformin is an insulin-sensitizing antidiabetic (biguanide). It lowers glucose production by the liver and improves peripheral uptake and utilization of glucose, helping reduce blood sugar without usually causing hypoglycaemia when used alone.

How to take Mediformin-SR Tablet

Oral sustained-release tablet. Take exactly as prescribed, usually once daily with or after the evening meal; swallow whole with water (do not crush, chew, or split). Take at the same time each day; if a dose is missed, take it when remembered unless it is near the next dose.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Mediformin-SR Tablet

Most side effects of Mediformin-SR are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• diarrhoea
• vomiting
• abdominal pain
• loss of appetite
• metallic taste
• flatulence
• headache
• weakness
• vitamin B12 deficiency (long-term)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Mediformin-SR Tablet

Warnings and precautions

Risk of lactic acidosis (rare but serious)—seek urgent care for rapid breathing, severe weakness, unusual muscle pain, stomach pain with vomiting, or feeling very cold. Use with caution in kidney disease; dose adjustment/avoidance may be needed and renal function monitoring is recommended. Avoid in severe liver disease, severe dehydration, acute heart failure, severe infection, or conditions causing low oxygen. Temporarily stop before/after iodinated contrast imaging or major surgery as advised. Monitor blood glucose and HbA1c regularly; long-term use may reduce vitamin B12—periodic monitoring may be needed.

Do not take Mediformin-SR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cimetidine, dolutegravir, ranolazine, diuretics and ACE inhibitors/ARBs (via effects on kidney function), corticosteroids and thyroid hormones (may raise glucose), other antidiabetics/insulin (may increase hypoglycaemia risk)

How to store Mediformin-SR Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original strip and out of reach of children.

Expert advice for Mediformin-SR Tablet

Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

VEE MEDI BIOTECH INDIA

Therapeutic class:

Antidiabetic

Drug class:

Biguanide (insulin sensitizer)