
Apresol Injection
Exeltis Ordain Health Care - Injection - 20mg - 1 ml
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Methylcobalamin (500mcg) + Pregabalin (75mg)
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This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹73
Megabid 75 is used for megabid 500mcg/75mg Capsule is used in the treatment of neuropathic pain.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Megabid 75 contains Methylcobalamin (500mcg) + Pregabalin (75mg). It belongs to the B-complex vitamin and Gabapentinoid class of medicines.
Megabid 500mcg/75mg Capsule is used in the treatment of neuropathic pain.
Megabid 500mcg/75mg Capsule is a combination of two medicines: Methylcobalamin/Mecobalamin and Pregabalin. Methylcobalamin/Mecobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megabid 500mcg/75mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Megabid are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Megabid 500mcg/75mg Capsule may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Megabid 500mcg/75mg Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Megabid 500mcg/75mg Capsule may cause excessive drowsiness and calmness with alcohol. |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Megabid 500mcg/75mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Megabid 500mcg/75mg Capsule may be needed. Please consult your doctor. |
| Liver | Megabid 500mcg/75mg Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Megabid 500mcg/75mg Capsule may not be needed in these patients. Please consult your doctor. |
| Habit forming | Yes |
Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for. Take the larger part of the dose at night if drowsiness is a problem. Rise slowly from sitting or lying, especially in the first weeks. Keep your review appointment so the dose can be adjusted to the lowest that controls your pain.
Medicines with the same active ingredient (Methylcobalamin (500mcg) + Pregabalin (75mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Megabid 75 |
|---|---|---|---|
| Peblin M 75 mg CapsuleMOVA PHARMACEUTICALS | capsule · 10`S | ₹223 | 205% more |

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The information on Megabid 75 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.