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Prescription requiredCipla LimitedAnti-ulcer agent
Neksium 40 mg Tablet
Esomeprazole (40mg)
₹230MRP ₹242In stock
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Neksium 40 mg Tablet is used for treatment of Gastroesophageal reflux disease (Acid reflux),Treatment of Peptic ulcer disease,Treatment of Zollinger-Ellison syndrome.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Esomeprazole (40mg)
Available variants: tablet 40 mg 15`S
Best price: ₹230 (₹15.30 per tablet)
MRP: ₹242
Prescription: Required
Manufacturer: CIPLA LIMITED
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
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Neksium 40 mg Tablet
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Same salt, different brand — what does that mean?
A substitute contains the same active ingredient (salt), in the same strength, as Neksium 40 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Composition of Neksium 40 mg Tablet
Neksium 40 mg Tablet contains Esomeprazole (40mg). It belongs to the Proton pump inhibitor class of medicines.
Uses of Neksium 40 mg Tablet
- Treatment of Gastroesophageal reflux disease (Acid reflux)
- Treatment of Peptic ulcer disease
- Treatment of Zollinger-Ellison syndrome
Key benefits
- Powerful and reliable relief of acidity
- Heals ulcers and reflux damage
- Usually taken once a day
How Neksium 40 mg Tablet works
Neksium 40mg Tablet is a proton pump inhibitor (ppi). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
How to take Neksium 40 mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neksium 40mg Tablet is to be taken empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Neksium 40 mg Tablet
Most side effects of Neksium are mild and settle as the body adjusts. Reported side effects include:
- Headache
- Dryness in mouth
- Nausea
- Abdominal pain
- Constipation
- Flatulence
- Diarrhea
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Neksium 40 mg Tablet
| Pregnancy | Information regarding the use of Neksium 40mg Tablet during pregnancy is not available. Please consult your doctor. |
|---|---|
| Breastfeeding | Information regarding the use of Neksium 40mg Tablet during breastfeeding is not available. Please consult your doctor.Caution should be exercised when Neksium 40mg Tablet is administered to breastfeeding women. |
| Alcohol | Caution is advised when consuming alcohol with Neksium 40mg Tablet. Please consult your doctor. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Neksium 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Neksium 40mg Tablet is recommended.However, due to lack of data, exercised should be caution in patients with severe renal insufficiency. |
| Liver | Neksium 40mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Neksium 40mg Tablet may be needed. Please consult your doctor.However, no dose adjustment is required for patients with mild to moderate liver disease. |
| Habit forming | No |
Warnings and precautions
Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.
Do not take Neksium if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Interactions with other medicines
Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.
How to store Neksium 40 mg Tablet
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Neksium 40 mg Tablet
Take it before breakfast, not after a meal. Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking — these do as much as the tablet for reflux.
Manufacturer and class
- Manufacturer:
- CIPLA LIMITED
- Therapeutic class:
- Anti-ulcer agent
- Drug class:
- Proton pump inhibitor
Substitutes for Neksium 40 mg Tablet
Medicines with the same active ingredient (Esomeprazole (40mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Neksium 40 mg Tablet |
|---|---|---|---|
| Olnex 40 TabletLIVIDUS PHARMACEUTICALS PVT LTD.` | tablet · 10`S | ₹69 | 70% cheaper |
| Esomefol 40 mg Tablet | 10 | ₹71 | 69% cheaper |
| Esomeg 40 mg TabletEAST WEST PHARMA | tablet · 10`S | ₹78 | 66% cheaper |
| Chexid Rf TabletARISTO PHARMACEUTICALS PVT LTD | tablet · 10S | ₹87 | 62% cheaper |
| Espanz 40 mg TabletICARUS HEALTHCARE | tablet · 10`S | ₹89 | 61% cheaper |
| Esohap 40 mg TabletSOLARIZ HEALTHCARE PVT LTD | tablet · 10`S | ₹91 | 60% cheaper |
| Coolgi 40 TabletSILOM | tablet · 15`S | ₹94 | 59% cheaper |
| Zosa Fast TabletZuventus Healthcare Ltd | tablet · 10`S | ₹94 | 59% cheaper |
| Esolembic 40 TabletALEMBIC PHARMA | tablet · 15`S | ₹94 | 59% cheaper |
| Espra 40 mg TabletZYDUS HEALTHCARE PHARMA | tablet · 10`S | ₹97 | 58% cheaper |
| Esogress 40 TabletLARENON | tablet · 15`S | ₹158 | 31% cheaper |
| Nexom 40 Tablet | 15'S | ₹162 | 30% cheaper |
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Neksium 40 mg Tablet FAQs
What is Neksium 40 mg Tablet used for?
Neksium 40 mg Tablet is commonly used for Treatment of Gastroesophageal reflux disease (Acid reflux),Treatment of Peptic ulcer disease,Treatment of Zollinger-Ellison syndrome. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Neksium 40 mg Tablet?
Neksium 40 mg Tablet contains Esomeprazole (40mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Neksium 40 mg Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Neksium 40 mg Tablet work?
Neksium 40mg Tablet is a proton pump inhibitor (ppi).
Is Neksium 40 mg Tablet a prescription medicine?
Yes. Neksium 40 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Neksium 40 mg Tablet?
The side effects reported most often with Neksium are Headache, Dryness in mouth, Nausea, Abdominal pain, Constipation. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Neksium 40 mg Tablet be taken during pregnancy?
Information regarding the use of Neksium 40mg Tablet during pregnancy is not available. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Neksium.
Can I drink alcohol while taking Neksium 40 mg Tablet?
Caution is advised when consuming alcohol with Neksium 40mg Tablet.
What if I miss a dose of Neksium 40 mg Tablet?
Take it as soon as you remember.
Is Neksium 40 mg Tablet habit forming?
No. Neksium 40 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Neksium 40 mg Tablet?
Olnex 40 Tablet has the same active ingredient and strength and is listed from ₹69 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Neksium 40 mg Tablet cost on PingMeDoc Pharmacy?
Neksium 40 mg Tablet starts at ₹230 (MRP ₹242) on PingMeDoc Pharmacy. Available in tablet 40 mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Neksium 40 mg Tablet?
Neksium 40 mg Tablet is manufactured by CIPLA LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Neksium 40 mg Tablet delivered?
Neksium 40 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Neksium 40 mg Tablet, Quick facts
- Salt
- Esomeprazole (40mg)
- Form
- tablet
- Best price
- ₹230 (₹15.30 per tablet)
- MRP
- ₹242
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- CIPLA LIMITED
- Manufacturer
- CIPLA LIMITED
- Therapeutic class
- Anti-ulcer agent
- Drug class
- Proton pump inhibitor
- Habit forming
- No
- Variants
- tablet 40 mg 15`S
- Delivery
- Standard across India
References
The information on Neksium 40 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Neksium 40 mg Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.