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Desvenlafaxine (50mg)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
You can pay now and add the prescription afterwards. We pack your order only after a pharmacist verifies it.
A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.
Nexvenla OD 50 mg Tablet is used for depression.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Nexvenla OD 50 mg Tablet.
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Nexvenla OD 50 mg Tablet
tablet - 50 mg - 10 S
₹202
₹20.22 per tablet
CIPLA LIMITED · tablet - 50 mg - 10 S · Rx
₹146
₹14.58 per tablet
LINUX LABORATORIES` · tablet - 50 mg - 10 S · Rx
₹156
₹15.65 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Nexvenla OD 50 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Nexvenla OD 50 mg Tablet contains Desvenlafaxine (50mg). It belongs to the Antidepressant class of medicines.
Depression
Nexvenla OD 50 Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nexvenla-OD 50 Tablet ER may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Nexvenla-OD 50 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Nexvenla OD are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Nexvenla OD 50 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Nexvenla OD 50 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Nexvenla OD 50 Tablet may cause excessive drowsiness and calmness with alcohol. |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Nexvenla OD 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nexvenla OD 50 Tablet may be needed. Please consult your doctor. |
| Liver | Nexvenla OD 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Nexvenla OD 50 Tablet may be needed. Please consult your doctor. |
| Habit forming | No |
These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Nexvenla-OD 50 Tablet ER helps in treating depression and anxiety. It may take 2 to 4 weeks for Nexvenla-OD 50 Tablet ER to start working. Keep taking it as prescribed. It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. Avoid consuming alcohol when taking Nexvenla-OD 50 Tablet ER as it may cause excessive drowsiness and increase the risk of liver damage. It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you. Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts. Do not stop taking the medication suddenly without talking to your doctor.
Medicines with the same active ingredient (Desvenlafaxine (50mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Nexvenla OD 50 mg Tablet |
|---|---|---|---|
| D-Venlor 50 mg TabletCIPLA LIMITED | tablet · 10`S | ₹146 | 28% cheaper |
| Venlite OD 50 mg TabletLINUX LABORATORIES` | tablet · 10`S | ₹156 | 23% cheaper |
| Ventab Dxt 50Intas Pharmaceuticals Ltd | 10`S | ₹222 | 10% more |

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The information on Nexvenla OD 50 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.