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Abbott India Limited - Sachet - 6 G
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Insulin Aspart (50%) + Insulin Aspart Protamine (50%)
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Novomix 50 Penfill is used for diabetes.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Novomix 50 Penfill contains Insulin Aspart (50%) + Insulin Aspart Protamine (50%). It belongs to the Insulin class of medicines.
Diabetes
Insulin aspart and insulin aspart protamine. Insulin aspart has a fast onset of action, while insulin aspart protamine has a prolonged duration of action. Together, they ensure rapid and consistent sugar control by facilitating the reuptake of sugar in muscle and fat cells and suppressing sugar production in the liver.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you have missed a dose of Novomix 50 100IU/ml Penfill, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.
An overdose of this medicine can cause severe low blood sugar, leading to fits or unconsciousness — this is a medical emergency. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Novomix are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy SAFE IF PRESCRIBED |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CAUTION |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Never change your insulin brand, strength or type on your own — always through your doctor. Rotate the injection site each time, or fatty lumps will form and the insulin will be absorbed unpredictably. Do not use insulin that has changed colour, gone cloudy when it should be clear, or has clumps in it. Never share a pen or needle, even with a family member.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not to be used during an episode of low blood sugar.
Beta blockers can mask the warning signs of low blood sugar. Steroids raise blood sugar and your insulin dose may need review.
Keep unopened insulin in the refrigerator between 2°C and 8°C — never in the freezer, and never against the ice box. The pen or vial in use may be kept below 30°C, away from direct sunlight, for the period stated on the pack. Keep out of the reach of children.
Take it 15 minutes before or within 20 minutes after starting a meal. Injection below the skin of the abdomen results in faster absorption than other injection sites, such as the skin of the upper arms, thighs, or buttocks. After injection, the site of injection should not be massaged. Injection sites must be rotated to prevent hard lumps from developing at one site. Change to another type or brand of insulin should be done under strict medical supervision as it may require a change in dosage. Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol, or by delaying/skipping a meal. Carry a sugar source with you for immediate relief. Do not share your insulin device with others, even if the needle has been changed. You may give other people a serious infection or get it from them. Opened vials/cartridges can be stored at room temperature for up to 4 weeks, while unopened vials must be stored in the refrigerator (2°C–8°C).

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The information on Novomix 50 Penfill is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.