Oleanz Plus

Composition of Oleanz Plus

Oleanz Plus contains Fluoxetine + Olanzapine. It belongs to the Antidepressant and Antipsychotic class of medicines.

Uses of Oleanz Plus

• This medicine is used in the treatment of depression
• anxiety
• obsessive compulsive disorder
• nerve pain
• migraine prevention
• schizophrenia
• bipolar disorder
• severe agitation and psychosis.

Key benefits

• Effective for depression and anxiety disorders
• Also relieves nerve pain and prevents migraine
• Usually taken once a day
• Controls psychosis and severe mood episodes
• Prevents relapse when taken consistently

How Oleanz Plus works

This medicine combines 2 active ingredients: Fluoxetine and Olanzapine. Fluoxetine restores the balance of the chemical messengers in the brain that regulate mood, sleep and the way pain is felt. Olanzapine rebalances the chemical messengers in the brain that, in excess, produce hallucinations, delusions and severe agitation.

How to take Oleanz Plus

Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. It can cause deep drowsiness, a severe fall in blood pressure, abnormal movements and heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Oleanz Plus

Most side effects of Oleanz Plus are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• Dry mouth
• Drowsiness or difficulty sleeping
• Headache
• Weight change
• Reduced sexual desire
• Constipation
• Drowsiness
• Weight gain
• Tremor
• Stiffness
• Restlessness
• Dizziness on standing up

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Oleanz Plus

Warnings and precautions

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle. Report any tremor, stiffness, restlessness or uncontrollable movements of the face, tongue or limbs to your doctor promptly — these can become persistent if not addressed. Seek emergency care for high fever with severe muscle stiffness, confusion and sweating. This is rare but life-threatening. These medicines can raise blood sugar, cholesterol and weight. Your doctor will monitor them — keep those appointments. Never stop suddenly; your doctor will reduce the dose gradually. Take care in hot weather — this group affects how your body regulates temperature.

Do not take Oleanz Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one. Your doctor will assess suitability if you have heart disease, Parkinson's disease or dementia.

Interactions with other medicines

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group. Alcohol and sedatives add to the drowsiness. Tell your doctor about any medicine that affects heart rhythm.

How to store Oleanz Plus

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Oleanz Plus

Give it a fair trial of several weeks, and keep your review appointments. Take it at the same time each day — at night if it makes you drowsy, in the morning if it disturbs sleep. Talking therapy alongside medicine works better than either alone for most people. Take it exactly as prescribed; most relapses follow a stopped medicine. Rise slowly from sitting or lying. Keep your weight, sugar and lipid checks.

Manufacturer and class

Manufacturer:

SUN PHARMA

Therapeutic class:

Antidepressant and Antipsychotic

Drug class:

Antidepressant and Antipsychotic