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Prescription requiredZydus Healthcare PharmaGYNAECOLOGICAL

Safkit Tablet

Fluconazole (150mg) + Azithromycin (1000mg) + Secnidazole (1000mg)

Safkit Tablet is used for syndromic treatment of vaginal discharge.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹89MRP ₹945% off₹22.25 per tablet
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Fluconazole (150mg) + Azithromycin (1000mg) + Secnidazole (1000mg)
Available variants: tablet 150mg + 1000mg + 1000mg 4`S
Best price: ₹89 (₹22.25 per tablet)
MRP: ₹94
Prescription: Required
Manufacturer: ZYDUS HEALTHCARE PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Safkit Tablet

Safkit Tablet contains Fluconazole (150mg) + Azithromycin (1000mg) + Secnidazole (1000mg). It belongs to the Systemic antifungal, Macrolide and Antibacterial agent class of medicines.

Uses of Safkit Tablet

Syndromic treatment of vaginal discharge

Key benefits

  • In Syndromic treatment of vaginal discharge Safkit 150 mg/1000 mg/1000 mg Tablet is used for the syndromic treatment of vaginal discharge
  • addressing multiple possible causes like fungal
  • bacterial
  • and parasitic infections. It helps relieve symptoms such as abnormal discharge
  • itching
  • and discomfort
  • promoting faster recovery.

How Safkit Tablet works

Safkit 150 mg/1000 mg/1000 mg Tablet is a combination of fluconazole, azithromycin, and secnidazole. It works by targeting different types of microorganisms responsible for vaginal infections. Fluconazole acts against fungal pathogens by disrupting their cell membrane, Azithromycin inhibits bacterial growth by interfering with protein synthesis, and Secnidazole is active against anaerobic bacteria and protozoa by damaging their DNA. Together, they help control mixed infections associated with vaginal discharge and support effective resolution of symptoms.

How to take Safkit Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Safkit 150 mg/1000 mg/1000 mg Tablet should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Safkit 150 mg/1000 mg/1000 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause vomiting, liver injury and heart rhythm disturbance. It can cause vomiting, hearing disturbance and heart rhythm changes. It can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Safkit Tablet

Most side effects of Safkit are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Safkit Tablet

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol UNSAFE
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney CAUTION
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

Fungal skin and nail infections need long courses — weeks for skin, months for nails. Stopping when it looks better is the commonest reason it returns. Your doctor may check your liver with a blood test during a long course. Report yellowing of the eyes or skin, dark urine or persistent nausea at once. Tell your doctor if you have heart failure before taking itraconazole. This group interacts with a great many medicines — give your doctor a complete list. Finish the whole course even after you feel better. Tell your doctor if you have a heart rhythm problem or take a medicine for one — this group can affect the heart's electrical timing. Report severe or watery loose motions during or after the course rather than treating them yourself. Do not drink any alcohol while taking metronidazole, ornidazole or tinidazole, or for the period after the course that your doctor states — the combination causes severe flushing, vomiting and a racing heart. Tetracyclines stain developing teeth and are avoided in young children and in pregnancy. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.

Do not take Safkit if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with active liver disease, and several are not for use in pregnancy. Itraconazole is not for people with heart failure. Not for anyone with a known allergy to macrolide antibiotics, or with certain heart rhythm disorders.

Interactions with other medicines

Interacts strongly with statins, some heart medicines, blood thinners and sedatives — some combinations must be avoided altogether. Acid-reducing medicines lower the absorption of itraconazole. Interacts with a long list of medicines, including statins, some heart medicines and blood thinners — tell your doctor everything you take. Antacids reduce absorption; separate them by a couple of hours. Antacids, iron, zinc and calcium reduce the absorption of tetracyclines — separate them by a couple of hours. Tell your doctor if you take a blood thinner.

How to store Safkit Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Safkit Tablet

Safkit 150 mg/1000 mg/1000 mg Tablet should be taken with food at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. It is advisable to stay hydrated and drink plenty of water to overcome medicine side effects. It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Safkit 150 mg/1000 mg/1000 mg Tablet affects you. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Manufacturer and class

Manufacturer:
ZYDUS HEALTHCARE PHARMA
Therapeutic class:
GYNAECOLOGICAL
Drug class:
Systemic antifungal, Macrolide and Antibacterial agent

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Safkit Tablet FAQs

What is Safkit Tablet used for?
Safkit Tablet is commonly used for Syndromic treatment of vaginal discharge. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Safkit Tablet?
Safkit Tablet contains Fluconazole (150mg) + Azithromycin (1000mg) + Secnidazole (1000mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Safkit Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Safkit Tablet work?
Safkit 150 mg/1000 mg/1000 mg Tablet is a combination of fluconazole, azithromycin, and secnidazole.
Is Safkit Tablet a prescription medicine?
Yes. Safkit Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Safkit Tablet?
The side effects reported most often with Safkit are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Safkit Tablet be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Safkit.
Can I drink alcohol while taking Safkit Tablet?
Alcohol UNSAFE
What if I miss a dose of Safkit Tablet?
If you miss a dose of Safkit 150 mg/1000 mg/1000 mg Tablet, take it as soon as possible.
Is Safkit Tablet habit forming?
No. Safkit Tablet is not known to be habit forming when taken as prescribed.
How much does Safkit Tablet cost on PingMeDoc Pharmacy?
Safkit Tablet starts at ₹89 (MRP ₹94) on PingMeDoc Pharmacy. Available in tablet 150mg + 1000mg + 1000mg 4`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Safkit Tablet?
Safkit Tablet is manufactured by ZYDUS HEALTHCARE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Safkit Tablet delivered?
Safkit Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Safkit Tablet, Quick facts

Salt
Fluconazole (150mg) + Azithromycin (1000mg) + Secnidazole (1000mg)
Form
tablet
Best price
₹89 (₹22.25 per tablet)
MRP
₹94
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ZYDUS HEALTHCARE PHARMA
Manufacturer
ZYDUS HEALTHCARE PHARMA
Therapeutic class
GYNAECOLOGICAL
Drug class
Systemic antifungal, Macrolide and Antibacterial agent
Habit forming
No
Variants
tablet 150mg + 1000mg + 1000mg 4`S
Delivery
Standard across India

References

The information on Safkit Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Safkit Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.