
Alfugress D Tab
Larenon - Tablet - 10mg + 0.5mg - 10 S
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Sitagliptin (100mg) + Glimepiride (1mg)
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Sitahenz G1 Tablet is used for treatment of Type 2 diabetes mellitus.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Sitahenz G1 Tablet contains Sitagliptin (100mg) + Glimepiride (1mg). It belongs to the DPP-4 inhibitor and Sulfonylurea class of medicines.
Treatment of Type 2 diabetes mellitus
Sitahenz G1 Tablet is a combination of two medicines: sitagliptin and glimepiride. Sitagliptin works by blocking the DPP-4 enzyme (dipeptidyl peptidase-4 inhibitor) and increasing the secretion of insulin from the pancreas. Glimepiride (sulfonylurea) releases more insulin by stimulating the pancreas. Together these two medicines help control blood sugar levels in patients with type 2 diabetes.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitahenz G1 Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Sitahenz G1 Tablet, contact your doctor as soon as possible. They will advise you on how to proceed, which may include rescheduling the missed dose.
An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Sitahenz G1 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CAUTION |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly. If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease.
Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose. Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Monitor your blood glucose regularly to ensure Sitahenz G1 Tablet is working effectively. It might lead to low blood sugar (hypoglycemia), particularly if you miss meals, work out more than normal, or consume alcohol. Always keep a source of quick-acting sugar on hand, like glucose tablets or juice, for situations of low blood sugar. Take Sitahenz G1 Tablet precisely as directed by your doctor. Missing doses or changing the dosage without discussing it with your doctor may result in inadequate blood sugar management.

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The information on Sitahenz G1 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.