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Pfizer Ltd - Tablet - 50 mg - 14 S
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Methylprednisolone (125mg)
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Solution Medrol 125 mg Injection is used for treatment of Allergic conditions Treatment of Systemic lupus erythematosus (SLE) Treatment of Skin disorders Treatment of Eye disorders Treatment of Rheumatic disorder.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Solution Medrol 125 mg Injection contains Methylprednisolone (125mg). It belongs to the Systemic corticosteroid class of medicines.
Treatment of Allergic conditions Treatment of Systemic lupus erythematosus (SLE) Treatment of Skin disorders Treatment of Eye disorders Treatment of Rheumatic disorder
Solu-Medrol 125 mg Injection is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you missed a dose of Solu-Medrol 125mg Injection consult your doctor.
An overdose of this medicine can cause weight gain, high blood sugar, bone thinning and suppression of the body's own steroid production when it is taken over a prolonged period. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Solution Medrol 125 mg Injection are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Solu-Medrol 125 mg Injection may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Solu-Medrol 125 mg Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby. |
| Alcohol | Interaction with alcohol is unknown. Please consult your doctor. |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Solu-Medrol 125 mg Injection is safe to use in patients with kidney disease. No dose adjustment of Solu-Medrol 125 mg Injection is recommended.<br>However, talk to your doctor if you have any underlying kidney disease. |
| Liver | There is limited information available on the use of Solu-Medrol 125 mg Injection in patients with liver disease. Please consult your doctor. |
| Habit forming | No |
Never stop a course of more than a few days suddenly. Your body stops making its own steroid while you take these, and abrupt withdrawal can cause a dangerous collapse. Your doctor will taper the dose. Tell any doctor treating you that you take steroids, and say so urgently if you develop a serious infection, injury or need surgery — you may need a higher dose to cope. Steroids raise blood sugar. If you have diabetes, monitor it more closely during a course. Long-term use thins bones, raises the risk of infection, cataract and glaucoma. Your doctor will monitor and may add bone protection. Chickenpox and measles can be severe in people on steroids — seek advice promptly after any contact.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an untreated systemic infection, except where the steroid is part of the treatment.
Anti-inflammatory painkillers together with steroids markedly raise the risk of stomach bleeding. Live vaccines are generally avoided during significant steroid treatment.
Store as printed on the carton — some injections need refrigeration and must not be frozen. Keep out of the reach of children.
Solu-Medrol 125mg Injection helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system. Do not use it more often or for longer than advised by your doctor. Solu-Medrol 125mg Injection can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat. Do not stop taking Solu-Medrol 125mg Injection suddenly without talking to your doctor first as it may worsen your symptoms.

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The information on Solution Medrol 125 mg Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.