
Amrolstar Cream
Oaknet Lifesciences - Cream - 0.25%W/W - 50 G
Save ₹27
Prescription required
Methylcobalamin (1500mcg) + Pregabalin (75mg)
Available at our pharmacy counter
This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹129
Supranerv P is used for treatment of Neuropathic pain.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Supranerv P contains Methylcobalamin (1500mcg) + Pregabalin (75mg). It belongs to the B-complex vitamin and Gabapentinoid class of medicines.
Treatment of Neuropathic pain
Supranerv-P Tablet SR is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B, which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha-2 delta ligand that decreases pain by modulating the calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Supranerv-P Tablet SR may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Supranerv-P Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Supranerv P are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Supranerv-P Tablet SR may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Avoid consuming alcohol when taking Supranerv-P Tablet SR, as it may cause excessive sleepiness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior. Do not stop taking the medication suddenly without talking to your doctor. Supranerv-P Tablet SR may cause weight gain. Exercise regularly and eat a balanced diet to manage it.
Medicines with the same active ingredient (Methylcobalamin (1500mcg) + Pregabalin (75mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Supranerv P |
|---|---|---|---|
| Diamyelin 50 CapsuleVENREDD PHARMA | capsule · 10`S | ₹93 | 28% cheaper |
| Axon Pg TabletNOUVELLE PHARMACEUTICALS | tablet · 10`S | ₹116 | 10% cheaper |
| Pregamerge M SR 75 mg TabletD EARTH PHARMACEUTICALS | tablet · 10`S | ₹133 | 3% more |
| Medineuron Pg SRMMC HEALTHCARE LTD | 10`S | ₹143 | 10% more |
| Pregabrit TabletElbrit LIfe Sciences | tablet · 10`S | ₹143 | 10% more |
| Meconerv P SR TabletMICRO LABS | tablet · 10S | ₹148 | 15% more |
| Eflin -M 75 TabletPROPEL HEALTH CARE | tablet · 10`S | ₹152 | 18% more |
| Pregadoc-M 75LUPIN LAB | 10`S | ₹201 | 56% more |
| Pregadoc M SR 75 mg TabletLUPIN LAB | tablet · 10`S | ₹203 | 57% more |
| Axogurd SRALEMBIC PHARMA | 10`S | ₹216 | 67% more |
| Rejunuron Dn TabletFourrts India Laboratories Pvt Ltd | tablet · 10`S | ₹223 | 73% more |
| Matilda Pg ERLUPIN LAB | 10`S | ₹245 | 90% more |

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The information on Supranerv P is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.