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Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Levodopa (150mg) + Carbidopa (37.5mg) + Entacapone (200mg)
Parkinson's disease
SynCAPONE 150 Tablet is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinson’s disease.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SynCAPONE 150 Tablet may be taken with or without food. Avoid SynCAPONE 150 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.
Common side effects of Syncapone 150 10S may include:

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