Syncapone 150

Composition of Syncapone 150

Syncapone 150 contains Levodopa (150mg) + Carbidopa (37.5mg) + Entacapone (200mg). It belongs to the Anti-dementia / anti-parkinsonian agent class of medicines.

Uses of Syncapone 150

Parkinson's disease

Key benefits

• In Parkinson's disease SynCAPONE 150 Tablet is a medicine that helps relieve symptoms of Parkinson's disease such as tremors
• muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

How Syncapone 150 works

SynCAPONE 150 Tablet is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinson’s disease.

How to take Syncapone 150

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SynCAPONE 150 Tablet may be taken with or without food. Avoid SynCAPONE 150 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of SynCAPONE 150 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe confusion, abnormal movements, a very slow pulse and collapse. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Syncapone 150

Most side effects of Syncapone are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Syncapone 150

Warnings and precautions

Never stop a Parkinson's medicine suddenly — this can cause a severe and dangerous deterioration. Dose timing matters a great deal in Parkinson's disease. Take it at exactly the times prescribed. Report sudden daytime sleep attacks, hallucinations, or new gambling, spending or other impulsive behaviour — these are recognised effects and the dose may need review. Rise slowly from sitting or lying; a drop in blood pressure on standing is common.

Do not take Syncapone if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will assess suitability if you have heart, eye or psychiatric conditions.

Interactions with other medicines

Anti-emetics such as metoclopramide and some antipsychotics can worsen Parkinson's symptoms. High-protein meals can reduce the absorption of levodopa — ask your doctor about timing.

How to store Syncapone 150

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Syncapone 150

You have been prescribed SynCAPONE 150 Tablet to treat your symptoms of parkinson's disease. Avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking this medicine as that can reduce the amount of medication absorbed by your body. It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Do not stop taking the medication suddenly without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating and confusion. Talk to your doctor in case you develop hallucinations or notice other changes in your behavior.

Manufacturer and class

Manufacturer:

SUN PHARMA

Therapeutic class:

NEURO CNS

Drug class:

Anti-dementia / anti-parkinsonian agent