Tosanib 5 Tablet

Composition of Tosanib 5 Tablet

Tosanib 5 Tablet contains Tofacitinib (5mg). It belongs to the Janus kinase (JAK) inhibitor class of medicines.

Uses of Tosanib 5 Tablet

Treatment of moderate to severe rheumatoid arthritis (RA) in adults; may also be prescribed for psoriatic arthritis and ulcerative colitis as per specialist advice and approved indications.

Key benefits

• Reduces joint pain and swelling in rheumatoid arthritis
• Improves physical function and reduces stiffness
• Helps control immune-mediated inflammation
• May reduce flare-ups and disease activity

How Tosanib 5 Tablet works

Tofacitinib is a Janus kinase (JAK) inhibitor. It blocks JAK enzymes involved in immune signaling, thereby reducing inflammatory cytokine activity and helping relieve joint pain, swelling and stiffness.

How to take Tosanib 5 Tablet

Take by mouth as prescribed by the doctor, usually once or twice daily. Can be taken with or without food; swallow whole with water. Do not stop abruptly; regular monitoring tests are required.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Tosanib 5 Tablet

Most side effects of Tosanib are mild and settle as the body adjusts. Reported side effects include:

• Upper respiratory tract infection
• headache
• diarrhoea
• nausea
• increased cholesterol
• elevated liver enzymes
• hypertension
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tosanib 5 Tablet

Warnings and precautions

Prescription-only immunosuppressant. Increased risk of serious infections (TB, herpes zoster, opportunistic infections); screen for TB and hepatitis before starting. Risk of blood clots, major cardiovascular events and malignancy may be increased in certain patients—use only under specialist supervision. Monitor CBC, liver function and lipids; avoid use in severe hepatic impairment. Not recommended with other potent immunosuppressants/biologics. Seek urgent care for fever, persistent cough, breathlessness, chest pain, leg swelling, unusual bruising/bleeding.

Do not take Tosanib if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Strong CYP3A4 inhibitors (ketoconazole, clarithromycin) may increase levels; strong CYP3A4 inducers (rifampicin, carbamazepine, phenytoin) may reduce effect; immunosuppressants/biologics (azathioprine, cyclosporine, tacrolimus, TNF inhibitors) increase infection risk; live vaccines should be avoided during therapy.

How to store Tosanib 5 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Tosanib 5 Tablet

Keep every monitoring blood test appointment. Carry a note of the medicine and its schedule, especially for weekly dosing.

Manufacturer and class

Manufacturer:

ERIS LIFE SCIENCES PVT LTD

Therapeutic class:

Immunosuppressant / Antirheumatic

Drug class:

Janus kinase (JAK) inhibitor