Skip to main content
PingMeDoc
Prescription requiredIcon PharmaPAIN ANALGESICS

Ultra Plus

Tramadol (37.5mg) + Paracetamol (325mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹118

Ultra Plus is used for moderate to severe pain.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Tramadol (37.5mg) + Paracetamol (325mg)
Available variants: NA 10`S
Best price: ₹118
MRP: ₹125
Prescription: Required
Manufacturer: ICON PHARMA

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Ultra Plus

Ultra Plus contains Tramadol (37.5mg) + Paracetamol (325mg). It belongs to the Opioid analgesic and Para-aminophenol derivative class of medicines.

Uses of Ultra Plus

Moderate to severe pain

Key benefits

  • In Moderate to severe pain Ultra Plus Tablet works by acting on the brain to alter pain perception and by blocking pain signals. This helps provide faster and more effective relief from intense pain. Timely pain control can improve mobility and support recovery. As a result
  • patients may experience greater comfort and improved ability to perform daily activities.

How Ultra Plus works

Ultra Plus Tablet is a combination of two medicines: Tramadol and Paracetamol which relieve severe pain. Tramadol is an opioid analgesic (pain reliever) which works by blocking the transmission of pain signals to the brain to lower pain perception. Paracetamol works by blocking the release of certain chemical messengers that cause pain.

How to take Ultra Plus

Take exactly as prescribed by your doctor.

Side effects of Ultra Plus

Most side effects of Ultra Plus are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ultra Plus

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding SAFE IF PRESCRIBED
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingYes

Warnings and precautions

Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. This is an opioid painkiller. It can cause dependence, and should be taken only for the period your doctor has specified. Never combine it with alcohol, sleeping tablets or other sedatives — together they can dangerously slow your breathing. Do not stop a long course abruptly; your doctor will reduce it gradually. Tell your doctor if you have epilepsy or take an antidepressant — tramadol can lower the seizure threshold and can raise serotonin dangerously in combination. Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five.

Do not take Ultra Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with severe liver disease, except under medical supervision.

Interactions with other medicines

Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it.

How to store Ultra Plus

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Ultra Plus

Consider taking Ultra Plus Tablet with milk or food to prevent stomach upset. Ultra Plus Tablet may cause drowsiness, dizziness, or slowed reaction time, particularly when you first start taking it. It is recommended to avoid driving or operating heavy machinery until you are certain how it affects you. Drink plenty of water and eat fiber-rich foods like fruits and vegetables to help prevent constipation, a common side effect of Ultra Plus Tablet. Do not drink alcohol while taking Ultra Plus Tablet. Alcohol combined with this medicine can cause extreme drowsiness or dangerously slow your breathing. During long-term treatment, your doctor may conduct regular blood tests to monitor your liver function. Inform your doctor if you have a history of heart disease, high blood pressure, liver disease, kidney disease, epilepsy, or any breathing problems before taking Ultra Plus Tablet. Do not stop taking Ultra Plus Tablet suddenly if you have been using it for more than a few days. Stopping it abruptly may lead to withdrawal symptoms such as anxiety, restlessness, sweating, insomnia, and gastrointestinal discomfort.

Manufacturer and class

Manufacturer:
ICON PHARMA
Therapeutic class:
PAIN ANALGESICS
Drug class:
Opioid analgesic and Para-aminophenol derivative

Substitutes for Ultra Plus

Medicines with the same active ingredient (Tramadol (37.5mg) + Paracetamol (325mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Ultra Plus
Tramasure Plus Rf TabletMANKIND (PHARMA)tablet · 10`S₹8330% cheaper
Tramand TabletCOGNYZON PHARMACEUTICALStablet · 10`S₹13312% more
Trabest TabletLUPIN LABtablet · 10`S₹13615% more
Ultrazac TabletZYDUS HEALTHCARE PHARMAtablet · 10`S₹14018% more
Tramef P Tablet15₹14119% more
UltramedPharmed Ltd15`S₹19161% more
Ultram TabletMICRO LABStablet · 15`S₹21380% more
Ifimol-T Tablet15'S₹22993% more
Ultracet TabletJohnson & Johnson Pvt Ltdtablet · 15 Tablet₹281137% more
See all substitutes and alternatives

More from Icon Pharma

View categories
6% offRx

Adrole .25 Tab

Icon Pharma - Tablet - 0.5mg - 10 S

₹50₹53

Save ₹3

Prescription required

Adrole 0.5
5% offRx

Adrole 0.5

Icon Pharma - 10 S

₹86₹91

Save ₹5

Prescription required

5% offRx

Adrole Xl 2 Tab

Icon Pharma - Tablet - 10 S

₹216₹228

Save ₹12

Prescription required

5% offRx

Amantad Er 129 Tab

Icon Pharma - Tablet - 10 S

₹223₹234

Save ₹11

Prescription required

Amantad Er 193 Tab
5% offRx

Amantad Er 193 Tab

Icon Pharma - Tablet - 10 S

₹272₹286

Save ₹14

Prescription required

Rx

Amicon 10MG

Icon Pharma - 10 mg - 10 S

₹24₹25

Save ₹1

Prescription required

8% offRx

Amicon 25MG

Icon Pharma - 25 mg - 10 S

₹24₹26

Save ₹2

Prescription required

Amicon 75MG
5% offRx

Amicon 75MG

Icon Pharma - 75 mg - 10 S

₹53₹56

Save ₹3

Prescription required

More in NSAID Painkillers

View categories
Aceco Ps Tab
5% offRx

Aceco Ps Tab

Lewin Healthcare - Tablet - 100mg + 325mg - 10 S

₹109₹115

Save ₹6

Prescription required

6% offRx

Alzolam 0.5

Sun Pharma - 10 S

₹46₹49

Save ₹3

Prescription required

Available in store

In-store
Anaflam-Th4 Tab
5% offRx

Anaflam-Th4 Tab

Albert David Ltd - Tablet - 100mg + 325mg + 4mg - 10 S

₹208₹219

Save ₹11

Prescription required

5% offRx

Atrest 25MG Tab

Centaur Pharmaceuticals Ltd - Tablet - 25 mg - 10 S

₹373₹393

Save ₹20

Prescription required

Briv Syrup
5% offRx

Briv Syrup

Dr Reddys Laboratories Ltd - Syrup - 10mg - 100 ml

₹424₹446

Save ₹22

Prescription required

Cismatrix Tab
5% offRx

Cismatrix Tab

Kalpa Health Care Pvt Ltd - Tablet - 10 S

₹190₹200

Save ₹10

Prescription required

5% offRx

Clonil 75 SR

Intas Pharmaceuticals Ltd - 15 S

₹252₹266

Save ₹14

Prescription required

Divalex Od - 250MG Tab
5% offRx

Divalex Od - 250MG Tab

Crescent Forumulations Pvt Ltd - Tablet - 250 mg - 10 S

₹100₹105

Save ₹5

Prescription required

Popular on PingMeDoc Pharmacy

View categories
Wysolone Dt 5 Tablet
9% offRx

Wysolone Dt 5 Tablet

Pfizer Ltd - Tablet - 15 Tablet

₹10₹11

Save ₹1

Prescription required

D9 Hairblendz Nutritional Hair Kit
5% off

D9 Hairblendz Nutritional Hair Kit

D9 Healthcare Llp - Kit

₹1,581₹1,664

Save ₹83

Vaseline Jelly 12GM

12 G

₹10
15% off

Artery Forceps 6"Cd.Pak

1*1

₹510₹600

Save ₹90

Rbx Aid Plaster

100 S

₹4
7% off

Funplay Condom Choco 3S

Funplay - 1*3*30

₹28₹30

Save ₹2

15% off

Adson Forceps

1

₹298₹350

Save ₹52

Rbx Aid Plaster New

1

₹4₹4

Ultra Plus FAQs

What is Ultra Plus used for?
Ultra Plus is commonly used for Moderate to severe pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Ultra Plus?
Ultra Plus contains Tramadol (37.5mg) + Paracetamol (325mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How does Ultra Plus work?
Ultra Plus Tablet is a combination of two medicines: Tramadol and Paracetamol which relieve severe pain.
Is Ultra Plus a prescription medicine?
Yes. Ultra Plus is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Ultra Plus?
The side effects reported most often with Ultra Plus are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Ultra Plus be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Ultra Plus.
Can I drink alcohol while taking Ultra Plus?
Alcohol UNSAFE
Is Ultra Plus habit forming?
Yes Take Ultra Plus only as directed and for the duration your doctor advises.
Is there a cheaper substitute for Ultra Plus?
Tramasure Plus Rf Tablet has the same active ingredient and strength and is listed from ₹83 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Ultra Plus cost on PingMeDoc Pharmacy?
Ultra Plus starts at ₹118 (MRP ₹125) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Ultra Plus?
Ultra Plus is manufactured by ICON PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Ultra Plus delivered?
Ultra Plus is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Ultra Plus, Quick facts

Salt
Tramadol (37.5mg) + Paracetamol (325mg)
Best price
₹118
MRP
₹125
Prescription
Required (Rx)
Schedule
Schedule H1
Brand
ICON PHARMA
Manufacturer
ICON PHARMA
Therapeutic class
PAIN ANALGESICS
Drug class
Opioid analgesic and Para-aminophenol derivative
Habit forming
Yes
Variants
NA 10`S
Delivery
Standard across India

References

The information on Ultra Plus is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Ultra Plus.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.