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Prescription requiredMsn LaboratoriesImmunomodulator (DMARD)

Upadoz 30 mg Tablet

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Upadoz 30 mg Tablet is used for treatment of moderate to severe rheumatoid arthritis; may also be prescribed for other immune-mediated inflammatory conditions as per specialist advice (e.g., psoriatic arthritis, ankylosing spondylitis, atopic dermatitis, ulcerative colitis) depending on approved indication and local labeling.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Available variants: tablet 30 mg 30`S
Best price: ₹3,999 (₹133.30 per tablet)
MRP: ₹4,209
Prescription: Required
Manufacturer: MSN LABORATORIES

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Uses of Upadoz 30 mg Tablet

  • Treatment of moderate to severe rheumatoid arthritis; may also be prescribed for other immune-mediated inflammatory conditions as per specialist advice (e.g.
  • psoriatic arthritis
  • ankylosing spondylitis
  • atopic dermatitis
  • ulcerative colitis) depending on approved indication and local labeling.

Key benefits

  • Reduces joint pain and swelling
  • Improves physical function and mobility
  • Controls autoimmune inflammation
  • Helps achieve/maintain remission or low disease activity
  • Oral once-daily treatment option

How Upadoz 30 mg Tablet works

Upadacitinib is a Janus kinase (JAK) inhibitor (preferentially JAK1). It reduces inflammatory signaling by blocking cytokine pathways involved in immune activation, thereby decreasing pain, swelling and disease activity.

How to take Upadoz 30 mg Tablet

Oral tablet. Take exactly as prescribed, usually once daily, at the same time each day, with or without food. Swallow whole with water; do not crush/chew. If a dose is missed, take as soon as remembered on the same day; do not double the next dose.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Upadoz 30 Tablet ER, please consult your doctor.

If you take too much

Taking more Upadoz than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Upadoz 30 mg Tablet

Most side effects of Upadoz are mild and settle as the body adjusts. Reported side effects include:

  • Upper respiratory tract infection
  • nasopharyngitis
  • nausea
  • abdominal pain
  • headache
  • acne
  • cough
  • fever
  • increased liver enzymes
  • increased cholesterol
  • herpes zoster

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Upadoz 30 mg Tablet

PregnancyNot recommended / Consult doctor (use effective contraception during treatment and for a period after stopping as per label).
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholUse with caution (may increase risk of liver-related side effects; limit alcohol).
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney CONSULT YOUR DOCTOR
LiverLiver CONSULT YOUR DOCTOR
Habit formingNo

Warnings and precautions

Prescription-only immunosuppressant. Increased risk of serious infections (including TB, herpes zoster and opportunistic infections); screen for TB and viral hepatitis before starting and monitor. Risk of blood clots (DVT/PE), major cardiovascular events and malignancy reported with JAK inhibitors—use caution in patients with risk factors. Monitor CBC (low lymphocytes/neutrophils/hemoglobin), liver enzymes and lipids; stop/withhold in severe abnormalities. Avoid live vaccines during treatment; update immunizations before starting. Use caution in hepatic impairment; dose adjustments/avoidance may be needed as per label. Seek urgent care for signs of infection, chest pain, shortness of breath, leg swelling, severe abdominal pain or black stools.

Interactions with other medicines

Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin) may increase levels; strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, St John’s wort) may reduce effect. Avoid combining with other potent immunosuppressants/biologics (e.g., other JAK inhibitors, TNF inhibitors, cyclosporine, azathioprine) unless directed by specialist. Live vaccines should be avoided.

How to store Upadoz 30 mg Tablet

Store below 30°C in a dry place, protected from light and moisture. Keep in original pack and out of reach of children.

Expert advice for Upadoz 30 mg Tablet

Before starting Upadoz 30 Tablet ER, the doctor will screen for infections, including tuberculosis, hepatitis B/C, and assess liver and renal function before initiating therapy. The doctor will monitor for signs of infection during treatment. Withhold therapy if a serious infection develops. Doctor administer necessary vaccinations before starting Upadoz 30 Tablet ER therapy. Avoid live vaccines during treatment. Tell your doctor about all medications you are taking to avoid potential drug-drug interactions. Inform your doctor if you currently smoke or have smoked in the past, as this medicine may increase the risk of certain cancers such as lymphoma or lung cancer.

Manufacturer and class

Manufacturer:
MSN LABORATORIES
Therapeutic class:
Immunomodulator (DMARD)
Drug class:
Janus kinase (JAK) inhibitor (JAK1 selective)
Chemical class:
Janus Kinase (JAK) inhibitors

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Upadoz 30 mg Tablet FAQs

What is Upadoz 30 mg Tablet used for?
Upadoz 30 mg Tablet is commonly used for Treatment of moderate to severe rheumatoid arthritis; may also be prescribed for other immune-mediated inflammatory conditions as per specialist advice (e.g., psoriatic arthritis, ankylosing spondylitis, atopic dermatitis, ulcerative colitis) depending on approved indication and local labeling. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
How should I take Upadoz 30 mg Tablet?
Oral tablet. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Upadoz 30 mg Tablet work?
Upadacitinib is a Janus kinase (JAK) inhibitor (preferentially JAK1).
Is Upadoz 30 mg Tablet a prescription medicine?
Yes. Upadoz 30 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Upadoz 30 mg Tablet?
The side effects reported most often with Upadoz are Upper respiratory tract infection, nasopharyngitis, nausea, abdominal pain, headache. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Upadoz 30 mg Tablet be taken during pregnancy?
Not recommended / Consult doctor (use effective contraception during treatment and for a period after stopping as per label). Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Upadoz.
Can I drink alcohol while taking Upadoz 30 mg Tablet?
Use with caution (may increase risk of liver-related side effects; limit alcohol).
What if I miss a dose of Upadoz 30 mg Tablet?
If you miss a dose of Upadoz 30 Tablet ER, please consult your doctor.
Is Upadoz 30 mg Tablet habit forming?
No. Upadoz 30 mg Tablet is not known to be habit forming when taken as prescribed.
How much does Upadoz 30 mg Tablet cost on PingMeDoc Pharmacy?
Upadoz 30 mg Tablet starts at ₹3,999 (MRP ₹4,209) on PingMeDoc Pharmacy. Available in tablet 30 mg 30`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Upadoz 30 mg Tablet?
Upadoz 30 mg Tablet is manufactured by MSN LABORATORIES. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Upadoz 30 mg Tablet delivered?
Upadoz 30 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Upadoz 30 mg Tablet, Quick facts

Form
tablet
Best price
₹3,999 (₹133.30 per tablet)
MRP
₹4,209
Prescription
Required (Rx)
Brand
MSN LABORATORIES
Manufacturer
MSN LABORATORIES
Therapeutic class
Immunomodulator (DMARD)
Drug class
Janus kinase (JAK) inhibitor (JAK1 selective)
Chemical class
Janus Kinase (JAK) inhibitors
Action class
Janus kinase inhibitors
Habit forming
No
Variants
tablet 30 mg 30`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. Manufacturer labeling/SmPC, established medical literature on upadacitinib (JAK inhibitors), regulatory safety communications, standard pharmacology references
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Upadoz 30 mg Tablet.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.