
Ace Revelol 25/2.5
IPCA Laboratories Ltd - 10 S
Prescription required
Metformin + Vildagliptin
Valdiff M 500 Tablet is used for this medicine is used in the treatment of type 2 diabetes.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Valdiff M 500 Tablet contains Metformin + Vildagliptin. It belongs to the Biguanide and DPP-4 inhibitor class of medicines.
This medicine is used in the treatment of type 2 diabetes.
This medicine combines 2 active ingredients: Metformin and Vildagliptin. Metformin lowers blood sugar by reducing the amount of glucose your liver releases and by helping your muscles respond better to your own insulin. It does not force your pancreas to make more insulin, which is why it rarely causes low blood sugar on its own. Vildagliptin lowers blood sugar by protecting the natural gut hormones that tell your pancreas to release insulin after a meal, so the effect is strongest when your sugar is highest.
Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or just after food. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Valdiff M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult your doctor before using this in pregnancy. |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis.
Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them.

IPCA Laboratories Ltd - 10 S
Prescription required
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Prescription required
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The information on Valdiff M 500 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.