Valparin Chrono 200 Tablet

Composition of Valparin Chrono 200 Tablet

Valparin Chrono 200 Tablet contains Sodium Valproate (133mg) + Valproic Acid (58mg). It belongs to the Anticonvulsant (valproate; GABA-enhancing agent) class of medicines.

Uses of Valparin Chrono 200 Tablet

• Epilepsy (partial and generalized seizures)
• Bipolar disorder (acute mania and maintenance
• as prescribed)
• Migraine prophylaxis (prevention)

Key benefits

• Helps control seizures
• Stabilizes mood in bipolar disorder
• Prevents migraine attacks
• Prolonged-release for smoother drug levels and convenient dosing

How Valparin Chrono 200 Tablet works

Valproate increases the level of the inhibitory neurotransmitter GABA in the brain and reduces abnormal neuronal firing. It also modulates voltage-gated sodium and calcium channels, helping stabilize electrical activity and prevent seizures/mood swings.

How to take Valparin Chrono 200 Tablet

Swallow tablet whole with water; do not crush/chew as it is prolonged-release. Take at the same time each day, preferably with food to reduce stomach upset. Dose and schedule are as prescribed; do not stop suddenly without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Valparin Chrono 200 Tablet CR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause deep unconsciousness, slowed breathing and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Valparin Chrono 200 Tablet

Most side effects of Valparin Chrono are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• abdominal pain
• indigestion
• diarrhea
• increased appetite
• weight gain
• tremor
• dizziness
• drowsiness
• hair loss
• headache
• elevated liver enzymes
• thrombocytopenia

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Valparin Chrono 200 Tablet

Warnings and precautions

Prescription medicine. Risk of severe liver injury (especially in young children and in the first 6 months), pancreatitis, and hyperammonemic encephalopathy—seek urgent care for severe abdominal pain, persistent vomiting, jaundice, unusual drowsiness/confusion. Teratogenic: high risk of major birth defects and neurodevelopmental disorders; avoid in pregnancy unless no alternative—effective contraception required for women of childbearing potential. Monitor liver function, blood counts, and valproate levels as advised. Use caution in liver disease, bleeding disorders, mitochondrial disorders (e.g., POLG mutations), and in elderly (sedation/falls). Do not discontinue abruptly (seizure risk).

Do not take Valparin Chrono if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Valproate-containing medicines are contraindicated in pregnancy for epilepsy unless no alternative exists, and in all women of childbearing potential without a pregnancy prevention programme. Several are not suitable in significant liver disease.

Interactions with other medicines

Carbamazepine, phenytoin, phenobarbital, lamotrigine (increased risk of serious rash—dose adjustment needed), topiramate (hyperammonemia), clobazam, benzodiazepines and other CNS depressants, aspirin/salicylates and anticoagulants/antiplatelets (bleeding risk), rifampicin, erythromycin, cimetidine, zidovudine, meropenem/imipenem (carbapenems reduce valproate levels markedly—avoid), alcohol

How to store Valparin Chrono 200 Tablet

Store below 25°C, protect from moisture and light, keep in original strip/container and out of reach of children.

Expert advice for Valparin Chrono 200 Tablet

Take it at the same time every day to maintain consistent levels in your body. Do not drive or do anything that requires mental focus until you know how Valparin Chrono 200 Tablet CR affects you. Avoid consuming alcohol when taking Valparin Chrono 200 Tablet CR, as it may cause excessive sleepiness or drowsiness. Monitor your weight during the treatment as Valparin Chrono 200 Tablet CR can cause weight gain. Your doctor may monitor the level of medicine in your body, your blood counts, and liver function regularly throughout your treatment. Inform your doctor if you develop fever, stomach pain, nausea, or yellowing of your eyes or skin. Do not take Valparin Chrono 200 Tablet CR if you are pregnant or planning to conceive or breastfeeding. Do not stop taking the medication suddenly without talking to your doctor, as it may increase the seizure frequency.

Manufacturer and class

Manufacturer:

CIPLA LIMITED

Therapeutic class:

Antiepileptic, Mood stabilizer, Antimigraine (prophylactic)

Drug class:

Anticonvulsant (valproate; GABA-enhancing agent)